Indap - a drug used to treat hypertension
 Indap - a drug for the treatment of hypertension.

Pharmacological action

Indap lowers blood pressure due to the fact that dilates blood vessels and has a diuretic effect.

Active substance Indap - indapamide, which contributes to accelerated elimination of chlorine and sodium, magnesium, potassium, selectively blocks calcium channels, increases the elasticity of the arterial wall reduces peripheral vascular resistance and left ventricular hypertrophy, vascular wall reduces sensitivity to noradrenaline, angiotensin II. On plasma levels of lipid indapamide not affected.

According to the instructions Indap high doses has no more pronounced hypotensive action, despite the fact that the volume of urine increases. Therapeutic effect develops in 1-2 weeks to reach its maximum 8-12 weeks and stored for about 8 weeks.

Product form

Indap release tablets, capsules.

Indications Indap

The drug is prescribed for the treatment of arterial hypertension.

Instructions Indap: how to use

 Indap capsules
 The tablets should preferably be taken in the morning.

Early treatment Indap designate a dosage of 1, 25-2, 5 mg, or 1, 5 mg if retard tablet. Take preparat1r / day.

If the expected treatment effect is not observed after one or two months to add Indap antihypertensives with different mechanism of action. Judging by the reviews of Indap increase the dosage in such cases is not recommended because it increases the risk of side effects.

Side effects Indap

Indap can cause diarrhea, abdominal pain, constipation, poor appetite, gastralgia, dry mouth, headache, drowsiness, dizziness, malaise, nervousness, anxiety, agitation, fatigue, asthenia, lethargy, drowsiness, depression, insomnia, conjunctivitis, chest pain, back, the deterioration of libido or potency, weight loss, increased sweating.

There are reviews Indap, causing runny nose, sinusitis, cough, arrhythmia, vasculitis, urticaria, pruritus, glucosuria, hypercalcemia, hyperglycemia, frequent infections.

In overdose begins vomiting, disturbed GI function, fluid and electrolyte balance, nausea, weakness, respiratory depression, low blood pressure.

In patients with cirrhosis of the liver due to the use Indap can begin hepatic coma. For treatment reduced the balance of electrolytes and water, washed with stomach, symptomatic treatment.


Indap contraindicated in hepatic / renal failure severe, hypokalemia, acute circulatory disorders of the brain, decompensated diabetes, lactose intolerance, malabsorption galactose / glucose.

Precautions Indap according to the instructions prescribed for moderate renal, hepatic failure, ischemia, chronic heart failure, ascites, hyponatremia, hyperuricemia, hyperparathyroidism, nursing, pregnant women, elderly patients, children up to 18L.

Keep in mind that during the doping control Indap can give a positive result.

Judging by the reviews of Indap, combined with lithium it is toxic to the kidneys.

The risk of renal dysfunction increases with simultaneous use Indap and contrast agents containing iodine. Hypokalemia may develop due to a combination of indapamide with cardiac glycosides, laxatives, tetrakozaktidom, amphotericin B. The combination of the drug with ACE inhibitors can cause hypotension or acute renal failure.

Indapamide reduces the effectiveness indandiona coumarin derivatives.

The hypotensive effect of the drug is increased tricyclic antidepressants, antipsychotics.

The simultaneous use of indapamide with cyclosporine may cause hypercreatininemia.