Ibuprofen - nonsteroidal synthetic drug with analgesic, anti-inflammatory and antipyretic activity.

Pharmacological action

The active substance of the preparation - ibuprofen phenylpropionic acid derivative.

Ibuprofen is most effective in inflammatory pain. By antipyretic effect is close enough to acetylsalicylic acid. It suppresses platelets from sticking together, improves microcirculation and reduces the intensity of inflammation.

When applied topically as an ointment Ibuprofen has a strong analgesic effect, reducing congestion, morning stiffness and swelling.

The drug is related to the list of essential medicines of the World Health Organization, its efficacy and safety researched and clinically tested.

Product form

Ibuprofen is available as tablets, suspensions and ointments.

  • Ibuprofen tablets - round, smooth, white biconvex. Each tablet contains 200 mg or 400 mg of active substance. Excipients - magnesium stearate, talc, lactose, potato starch, colloidal silicon dioxide, povidone 25. 10, 20 and 100 pieces per pack;
  • The coated tablet Ibuprofen depot. Each tablet contains 800 mg of active substance. 7, 14, and 60 pieces in a package;
  • Lozenges. Each tablet contains 200 mg active ingredient;
  • Capsules depot. Each capsule contains 300 mg of active ingredient;
  • Ibuprofen Suspension for oral homogeneous, yellow, orange-scented. 5 ml of suspension contains 100 mg of active substance. Available in bottles of 100 ml, in a cardboard box with a measuring spoon;
  • 5% cream and gel for external use.

Indications Ibuprofen

Ibuprofen is indicated for:

  • Symptomatic treatment of influenza and SARS;
  • Osteoarthritis;
  • Psoriatic arthritis;
  • Cervical spondylosis;
  • Barre Syndrome-Leu;
  • Shane migraine;
  • Bursa;
  • Ankylosing spondylitis;
  • Neuralgic amyotrophy;
  • Myalgia;
  • Nephrotic syndrome;
  • Postural hypotension (when taking antihypertensive agents);
  • Febrile states of various etymologies;
  • Traumatic inflammation of soft tissue and musculoskeletal system;
  • Vertebral artery syndrome;
  • Neurology;
  • Tendonitis;
  • Hematoma.

Ibuprofen is also indicated in the treatment of sprains ligaments, rheumatoid arthritis, sciatica, and articular syndrome (an exacerbation of gout).

As an aid Ibuprofen is indicated for use in:

  • Pneumonia;
  • Postoperative, dental, and headache;
  • Infectious-inflammatory diseases of ENT - pharyngitis, tonsillitis, rhinitis, laryngitis, sinusitis;
  • Bronchitis;
  • Panniculitis;
  • Primary dysmenorrhea;
  • Algodismenoree;
  • Inflammatory processes in the pelvis;
  • Adnexitis.


Ibuprofen is contraindicated in the instructions for:

  • Hypersensitivity to the drug;
  • Acute gastric ulcer or duodenal ulcer, and ulcerative colitis;
  • Diseases of the optic nerve and impaired color vision;
  • "Aspirin" asthma;
  • Hypertension;
  • Scotoma;
  • Amblyopia;
  • Severe impaired renal function or liver, as well as in liver cirrhosis with portal hypertension;
  • Congestive heart failure;
  • Swelling;
  • Hemophilia;
  • Anticoagulation;
  • Leukopenia;
  • Pathology of the vestibular apparatus;
  • Lack of glucose-6-phosphate dehydrogenase;
  • III trimester of pregnancy.

According to the instructions Ibuprofen is prescribed with caution in:

  • Chronic heart failure,
  • Concomitant diseases of the liver and kidneys,
  • Enteritis;
  • Immediately after surgery;
  • When dyspeptic symptoms prior to treatment;
  • Gastritis;
  • Colitis;
  • Children under 12 years old.

When ibuprofen is necessary to systematically monitor patterns of peripheral blood and the liver and kidneys.

Instructions for use of ibuprofen

 Ibuprofen Tablets

According to the instructions Ibuprofen taken after meals inside.

The daily dose depends on the disease:

  • Osteoarthritis, algodismenoree, psoriatic arthritis and ankylosing spondylitis adults appoint 400-600 mg 3-4 times a day;
  • In rheumatoid arthritis take larger dose of 800 mg three times a day;
  • When soft tissue injuries and sprains used ibuprofen tablets prolonged action-1600-2400 mg once a day, preferably before bedtime;
  • With moderate pain syndrome taking 1,200 mg per day;
  • With feverish syndrome arising after immunization used 50 mg, if necessary, you can repeat after 6 hours but not more than 100 mg per day.

With feverish conditions for children over 12 years to reduce the temperature of the body dose of Ibuprofen is calculated:

  • Above 39.2 degrees C - 10 mg per 1 kg of body weight per day;
  • Below 39.2 degrees C - 5 mg per 1 kg of body weight per day.

Ibuprofen Tablets for resorption are used to treat ENT diseases, dissolving in the mouth under the tongue. Children over 12 and adults appoint 200-400 mg 2-3 times a day.

A suspension for oral administration are usually administered to children. The average single dose at reception 3 times per day is:

  • From 1 to 3 years - 100 mg;
  • From 4 to 6 years - 150 mg;
  • From 7 to 9 years - 200 mg;
  • From 10 to 12 years - 300 mg.

Topically applied gel or cream Ibuprofen, striking and rubbing it until completely absorbed in the affected area 3-4 times a day. Treatment may be carried out in 2-3 weeks.

side effects

According to the instructions Ibuprofen - quite safe drug and is generally well tolerated. In the application may experience some side effects:

Digestive system: frequently occur diarrhea, nausea, vomiting, anorexia, diarrhea, epigastric discomfort, erosive and ulcerative lesions of the gastrointestinal tract; much less human liver or bleeding from the gastrointestinal tract.

Nervous system: may cause headache or dizziness, sleep disturbance or agitation, as well as visual impairment.

Circulatory system: the side effects are observed only after prolonged use of the drug - thrombocytopenia, anemia, agranulocytosis.

Urinary system: renal dysfunction may occur with long-term use of ibuprofen.

Allergic reactions can be observed when receiving the drug inside, and when applied topically in the form of redness, skin rash, angioedema, burning sensation. Much less bronhospastichesky occur and aseptic meningitis syndrome.

Ibuprofen is contraindicated in the III trimester of pregnancy. Application in I and II trimesters possible strictly by the physician.

During lactation Ibuprofen can be used in low doses for pain and fever. Because the drug is released in breast milk used in doses above 800 mg daily is contraindicated.

storage conditions

Ibuprofen is sold by prescription. Shelf life - 3 years.