Gramicidin - an antibacterial agent tirotritsinovoy group for local use. Widely used in ophthalmology, dentistry and ENT practice.

Pharmacological action

It is an antibiotic, gramicidin bacteriostatic and bactericidal activity against pathogens anaerobic infections, as well as staphylococci, meningococci, streptococci and pneumococci and other bacteria.

The active ingredient - gramicidin S.

Product form

The drug is released in the form:

  • Ampoule 2, 5 and 10 ml;
  • Paste 30 g cans or aluminum tubes. The composition includes a 2% solution of gramicidin C, lactic acid 40%, distilled water and an emulsifier;
  • Lozenges containing 1, 5 mg gramicidin S. Excipients - milk sugar, sugar, calcium stearate and methylcellulose. 10 or 20 pieces per pack.


According to the instructions gramicidin used in the treatment of:

  • Stomatitis;
  • Gingivitis;
  • Cellulitis;
  • Skin burns at different stages;
  • Conjunctivitis;
  • Abrasions;
  • Carbuncles;
  • Purulent wounds of soft tissues;
  • Pyoderma;
  • Keratitis;
  • Osteomyelitis;
  • Blepharitis;
  • Bedsores;
  • Inflammatory diseases of the vagina and cervix.

Also, the drug is used as a local contraceptive.

Instructions for use of gramicidin

Gramicidin apply:

In paste form:

Sterile gauze coated with the drug is applied to the wound surface. Changed every 2-4 days.

As contraceptive 5-6 g of the drug is introduced into the vagina a special syringe.

According to the instructions gramicidin contraindicated in dermatoses. It causes little pain on contact with the epithelium devoid of burn surface. In rare cases, there are a variety of allergic reactions such as itching, edema, urticaria and rashes.

In a solution:

Pre Gramicidin S solution is diluted 1: 100 with sterile distilled water or normal boiling. Used in purulent metritis and vaginitis ihoroznym douching, and tampons to soak, rinse, wash, irrigation bandages. The aqueous solution is stored for 3 days after preparation.

If necessary, it is possible to prepare such an alcoholic solution using 70% alcohol.

Dilute the contents of one ampoule is 25-30 times in either the purified vegetable oil (either fish oil or lanolin) can be prepared oil solution.

 Gramicidin pills
 In the form of tablets:

Tablets gramicidin widely used for the treatment and prevention of diseases of the throat. For this purpose two tablets (one after another) resolves not more than 4 times per day. If improvement is not fulfilled within 5 days, the drug should be discontinued.

Contraindications for use include tablets gramicidin hypersensitivity to the drug and allergic reactions.

When combined treatment should be borne in mind that gramicidin enhances the effect of the use of other microbicides.

During pregnancy and lactation the use of the drug is undesirable. On the interaction of alcohol with no data.