Gliclazide - hypoglycemic agents.
Gliclazide is a second-generation sulfonylureas.
The drug affects the carbohydrate metabolism, microcirculation, stimulates the production of insulin, increases the sensitivity to peripheral tissues, reduces the interval between ingestion and the onset of insulin.
Gliclazide restores the permeability of blood vessels, prevents the development of mikrotromboza, atherosclerosis, thrombosis delays the appearance of the wall.
There are reviews of gliclazide, that it does not lead to weight gain, even contributes to its reduction, subject to certain diet.
Producing Gliclazide tablets of conventional and modified release.
Gliclazide prescribed for adults for the treatment of diabetes mellitus of second type in cases where the exercise, special diet and weight loss did not have the desired effect.
Instructions for use of gliclazide
Gliclazide is taken orally with meals, starting with a dose of 80mg. Acceptable daily intake specified by the gliclazide - 160-320mg (take in two, usually in the morning, evening).
More precise dosage determined by the physician depending on the condition of the patient's age, blood concentrations of glucose.
The tablets of gliclazide modified release (usually 30 mg) taken once p / day in the morning during meals. If the drug was missed, the next day do not increase the dose.
The initial dose of gliclazide - 30mg. Change the dose can be no earlier than two weeks. Permissible daily dose - 120mg.
When Gliclazide overdose can cause hypoglycemia. In some cases, use of the drug leads to anemia, thrombocytopenia, leukopenia, agranulocytosis.
There are reviews of gliclazide, that after his admission observed nausea, diarrhea, pain in the epigastric region, anorexia, vomiting, itching, skin rash.
As indicated in the instructions Gliclazide not take the drug if you are hypersensitive, diabetic diabetes first type, diabetic ketoacidosis, coma, diabetic precoma, severe renal, hepatic insufficiency, during lactation, pregnancy.
It is impossible to prescribe a drug for children up to 18L.
Be wary appoint elderly Gliclazide, alcoholism, with clinical conditions that often require administration of insulin - extensive injuries and burns, major surgery, infection, accompanied by a feverish syndrome.