Gerpferon (Herpferon) - combined antiviral drug, marketed in the form of an ointment for topical treatment of herpes infections.
Structure and Composition
Gerpferon ointment comprising acyclovir (antiviral), interferon-α-2b, recombinant human (immunomodulatory agent), lidocaine hydrochloride (topical anesthetic) and adjuvants (methyl parahydroxybenzoate, macrogol). Ointment White (creamy tint allowed) with a specific smell blurred.
According to the instructions Gerpferona 1 g of ointment contains 30 mg of acyclovir, interferon 20000ME and 10 mg of lidocaine.
Available Gerpferon ointment in aluminum tubes for 5, 10 and '30 carton contains one tube and the instructions for use of the drug.
Pharmacological action Gerpferona
According to the instructions Gerpferon possesses antiviral, immunomodulatory and local analgesic effect. Interferon-α-2b recombinant human has antiviral activity (it inhibits the division of virus infected cells), but also has immunomodulatory effect.
Acyclovir has a pronounced antiviral effect against herpes virus (Herpes Simplex type 1 and 2), which causes chicken pox and shingles. Lidocaine has a local anesthetic effect and relieves itching.
The combination of these substances in Gerpferone provides pronounced antiviral effect (against the herpes virus), prevents the appearance of new lesions, accelerates healing and reduces pain and itching.
This product is intended for local and external use. Gerpferona absorption into the blood when the intact skin - minimum (the drug is not determined in the blood or urine), and lesions of the skin absorption of the drug is moderate.
- primary and repeated (recurrent) lesions of the skin and mucous herpes simplex virus;
- genital herpes;
Hypersensitivity to the ingredients of the preparation.
Dosing and Administration Gerpfrona
According to the instructions Gerpferon should be applied thinly to the affected areas of skin / mucous membranes 5 times a day, with an interval of 4 hours.
The course of treatment is 5-10 days. With the disappearance of the skin lesion / mucous frequency of use of the drug is reduced.
Use during pregnancy and lactation
Clinical studies on the use of the drug during pregnancy and lactation has not been carried out. Therefore, according to the instructions Gerpferon can be used in this group of patients only when the effect of the treatment of the disease outweighs the risk of possible negative effects.
Prolonged use of this ointment may cause flaking of the skin.
In the opinion of Gerpferona peeling occurs infrequently and is expressed slightly.
No data on cases of overdose of the drug.
Interaction with other drugs
According to the instructions Gerpferon well with anti-inflammatory and immunomodulatory drugs.
The effectiveness of treatment with this drug, the higher the sooner treatment is started.
In the opinion of Gerpferon should be used immediately after the first symptoms of the disease, to prevent the development of local changes. The drug does not affect the ability to drive or to perform work requiring high concentration.