Furadonin - a drug from the group of nitrofurans, which violates the permeability of cell membranes and protein synthesis in bacteria, providing
bactericidal, bacteriostatic effect. The product contains the active ingredient - nitrofurantoin. Has activity against the following microorganisms: Staphylococcus spp., Streptococcus spp., Salmonella paratyphi B, Salmonella paratyphi A, Salmonella typhi, Enterobacter spp., Escherichia coli, Proteus, Shigella sonnei. In clinical studies, showed a high antibacterial efficacy furadonin.
The instructions to furadonin indicated such indications for use:
- treatment of infectious and inflammatory diseases of the urinary tract caused by microorganisms sensitive to furadonin: pyelitis, pyelonephritis, urethritis, cystitis;
- prevention of infectious diseases during urological surgery, cystoscopy, catheterization.
According to the instructions furadonin, the drug is contraindicated in:
- hypersensitivity to nitrofurantoin;
- congestive heart failure;
- chronic renal failure;
- cirrhosis of the liver;
- chronic hepatitis;
- acute porphyria;
- deficiency of glucose-6-phosphate dehydrogenase;
- pregnancy, lactation;
- under the age of 1 month.
Furadonin for oral administration. It produced the drug in tablet form. It is recommended to wash down pill furadonin plenty of water. A single dose furadonin is 0, 1-0, 15g. Multiplicity of reception - 3-4 times a day. The maximum daily dose of 0, 6 r, single - 0, 3. The average duration of treatment - 7 days. The dosage in a particular clinical situation, as well as the duration of treatment determined by the doctor. The dosage in the case of prophylactic application antirecurrent and from 1 to 2 mg / kg. By indications furadonin can be assigned in pediatric dosage of 5 to 8 mg / kg per day. The daily dosage is administered in four divided doses.
When using furadonin reported allergic reactions (rash, lupus syndrome, arthralgia, myalgia, eosinophilia, angioedema, anaphylaxis), vomiting, nausea, dizziness, headache, fatigue, nystagmus, shortness of breath, bronchial obstruction syndrome, interstitial lung tissue changes, fever, drowsiness, pain in the chest, coughing, pancreatitis, hepatitis, cholestatic syndrome, peripheral neuropathy, pseudomembranous enterocolitis. It is rarely mentioned the appearance of erythema multiforme, abdominal pain.
sometimes are the cause of the negative reviews furadonin from patients, but when using the drug according to instructions and under medical supervision, he is quite well tolerated, and side effects of light do not require discontinuation of therapy.
Application furadonin during pregnancy
The drug furadonin contraindicated in pregnancy, lactation. If necessary, treatment furadonin lactation recommended to decide on the termination of breastfeeding.
Interaction with other drugs furadonin
With simultaneous use of antacids (containing magnesium trisilicate) and nalidixic acid decreased the antibacterial effect furadonin. Do not use furadonin fluoroquinolone antibiotic. When using drugs that block tubular secretion, reduced antibacterial effect by reducing the concentration of the drug in urine. It also enhances the toxicity furadonin.
In overdose furadonin develops vomiting. In the treatment of overdose of this drug is effective hemodialysis and forced diuresis.
Reviews furadonin from patients and doctors are positive, as the drug is highly effective in infectious diseases of the urinary tract, and the rational use of an adequate dosage furadonin safe.
The drug furadonin must be stored at room temperature out of reach of children.
When using furadonin in treating patients suffering from anemia, diabetes, electrolyte imbalance, hypovitaminosis B, it increases the likelihood of developing peripheral neuropathy.
Furadonin not used to treat septic paranephritis, prostate, and renal cortical pathology.
To reduce the risk of side effects from the gastrointestinal tract is recommended to take the drug together with food or milk.
Before using the drug to study the instructions in the furadonin. The use of this drug can only be prescribed by a doctor.