Latin name Fluimucil
Release form and composition of Fluimucil
The drug comes in the form of a clear solution for inhalation with a slight sulfur smell. Active substance - Acetylcysteine 1 ml per 100 mg. Other ingredients: water, disodium edetate, sodium hydroxide.
Fluimucil refers to mucolytic drugs. The active substance acetylcysteine breaks the disulfide bonds of acid mucopolysaccharides sputum, and thus reduces the viscosity of mucus. The drug remains active even in respect of purulent sputum. Acetylcysteine possesses anti-inflammatory and antioxidant effect, which is caused by the presence of a nucleophilic thiol group SH, neutralizing oxidising radicals which are responsible for the inflammatory processes in the tissues.
Acetylcysteine prevents reduction stock glutathione and helps increase its synthesis, thus facilitating detoxification. Due to this effect the drug Fluimucil can be used as an antidote for poisoning by paracetamol. Fluimucil easily penetrates into cells, where deacetylated to L-cysteine, which is then synthesized from glutathione - a powerful antioxidant and free radical scavenging toxins.
When taken orally, the drug is well absorbed Fluimucil. Due to the high effect of "first pass" bioavailability is about 10 percent. Like its analogs Fluimucil easily penetrates into the extracellular space and is distributed mainly in the bronchial secretions, kidneys, liver and lungs.
The drug and its metabolites are excreted in the kidneys, a small amount of output unchanged through the intestines. After receiving 600 mg Fluimucil maximum plasma concentration is reached within an hour and is 15 mmol / l.
The drug is prescribed for respiratory diseases, accompanied by labored expectoration: pneumonia, bronchiolitis, bronchitis, bronchiectasis, tracheitis, emphysema, lung abscess, cystic fibrosis, laryngotracheitis, interstitial lung disease, asthma, pulmonary atelectasis.
Showed Fluimucil in catarrhal and purulent otitis, sinusitis, sinusitis to improve discharge of secretions. It is also used for the removal of viscous mucus from the respiratory tract in post-traumatic and postoperative conditions.
Fluimucil Guide: how to use
Fluimucil granules: granules dissolved in 1/3 cup of water.
Newborn possible appointment for health reasons under the supervision of a physician. The dosage of 10 mg per 1 kg weight. Children from 1 year to 2 years, taking 100 mg twice daily. Children from 2 to 6 years of drug is given 2-3 times daily and 100 mg. Children from 6 years and adults prescribed dose 2-3 times a day 200 mg.
Duration of therapy is evaluated as a patient in acute diseases - the course is generally up to 10 days for chronic conditions - on prescription rate can last for several months.
Fluimucil effervescent tablets: one tablet dissolved in 1/3 cup of water. Enough solution single dose during the day. In acute states of therapy is 5-10 days for chronic conditions can last for several months.
Fluimucil injection: intended for parenteral use, are administered intravenously or intramuscularly. Adult patients administered 300 mg 1-2 times a day. Children 6-14 years, the recommended dose is half the adult dose. Children under 6 years of age the dosage is set at the rate of 10 mg per 1 kg of body weight.
The duration of therapy is established physician in response to changes in the patient's condition. High overall tolerance of the drug allows for prolonged courses of therapy.
Fluimucil inhalation solution made with 300 mg of the drug 1-2 times a day for 5-10 days. The dosage and frequency of administration can vary depending on the outcome of therapy.
Side effects of Fluimucil
Like its counterparts, Fluimucil, in rare cases has side effects such as: nausea, vomiting, diarrhea, hives, itching, skin rash, nasal bleeding, tinnitus. Data taking Fluimucil reviews show the possibility of developing on the background of his admission collapse, reduce platelet aggregation, bronchospasm, stomatitis.
When Fluimucil injections may cause a skin rash and a burning sensation at the injection site. Fluimucil inhalation may cause: a reflex cough, stomatitis, rhinitis, local irritation of the respiratory tract, in exceptional cases, bronchospasm (bronchodilators removed).
According to the instructions Fluimucil contraindicated:
- patients with gastric ulcer and 12 duodenal ulcer during the exacerbation;
- if you are hypersensitive to acetylcysteine or any other component of the drug;
- Children up to 18 years (as Fluimucil effervescent tablets).
Application Fluimucil pregnancy and during breast-feeding is permissible only after assessing the likely benefit ratio for mother and possible risk for the baby.
Fluimucil Interaction with other drugs
As received from the medical reviews Fluimucil, combined with other medications for cough, can cause stagnation of phlegm due to the suppression of the cough reflex.
Combining unparalleled Fluimucil with nitroglycerin can strengthen the vasodilator effect of the latter.
Simultaneous treatment with amphotericin B, ampicillin, tetracycline can lead to reduced activity of both drugs. Between taking these preparations and Fluimucil instructions recommended interval of at least two hours.
When you receive a dose of 500 mg / kg per day Fluimucil reviews about the symptoms or signs of overdose have been received.
According to the instructions, Fluimucil stored at room temperature, away from children. After opening the vial is allowed to store it in the refrigerator for no more than a day. Use the previously opened vials of the drug is prohibited.