Flemoksin soljutab - is an antibiotic from the group of semi-synthetic penicillins, with a wide spectrum of action. The active ingredient - amoxicillin trihydrate. The drug has a bactericidal effect.
Flemoxin Solutab possesses higher activity against many microorganisms, in particular S.pneumoniae, Staphylococcus aureus, Moraxella catarralis, Streptococcus pyogenus, Staphylococcus spp, Neisseria gonorrhoeae, Clostridium tetani, N.meningitidis, Bacillus anthracis, Haemophilus influenzae, Listeria monocytogenes, Helicobacter pylori, and somewhat less effective against some pathogens of intestinal infections: Escherichia coli, Enterococcus faecalis, Shigella sonnei, Proteus mirabilis, Salmonella typhi, Vibrio cholere. Flemoxin Solutab analogues and the drug inactive against bacteria that produce beta-lactamase.
Flemoxin Solutab has the ability to rapidly absorbed from the gastrointestinal tract after oral administration, the maximum concentration of active compound in plasma is achieved in 1-2 hours. When receiving the form of the drug, a higher concentration of amoxycillin plasma than using insoluble forms.
The active ingredient of the drug Flemoksin soljutab of 20% bound to plasma proteins. The therapeutic dose of the drug accumulates in bone tissue, sputum, intraocular fluid, mucous. The concentration of drug in the bile is 2-4 times higher than in blood. In liquid concentrates meningeal not more than 20% of the plasma content of the active ingredient.
Withdrawal Flemoksin soljutab and analogues takes place exclusively by the kidneys. Approximately 90% of amoxicillin is excreted in the urine within 8 hours after ingestion. By reducing creatinine clearance below 15ml / min half-life of the active substance is considerably increased, up to 8, for 5 hours at anuria.
The drug can be used in children since the age of 1 year, and given its high efficiency pediatricians give good reviews about flemoksin soljutab.
Indications flemoksin soljutab
Flemoksin soljutab used for the following diseases caused by susceptible organisms to the active substance:
- infections of the respiratory system,
- gastrointestinal diseases,
- urinary tract infection,
- infectious diseases of soft tissues and skin.
Flemoksin soljutab: instructions for use
According to the instructions Flemoksin soljutab can be taken regardless of the meal. A tablet may be swallowed or wholly or previously divided into parts. Wash down with plenty of water. It is also possible to dissolve the tablet in 200ml of water, forming a suspension with a citrus flavor.
In mild and moderate infectious diseases recommended Flemoksin soljutab in the following doses:
- for adults and children from 10 years: 500-750mg twice daily or 500 mg three times a day;
- Children 3-10 years: 250mg three times a day;
- for children 1-3 years: 250mg twice a day or 150 mg three times a day.
The average daily intake for children is 30 mg / kg.
In severe infectious diseases, as well as in the case of chronic disease and relapse the dose can be increased.
In each clinical situation, the dosage of the drug Flemoksin soljutab and analogues determined by the attending physician.
Duration of flemoksin soljutab
According to the instructions Flemoksin soljutab with infections of mild or moderate severity take 5-7 days, in the case of infections caused by streptococcus, - not less than 10 days.
In severe infections and chronic disease duration of reception flemoksin soljutab and analogues depends on the course of the disease.
Contraindications flemoksin soljutab
The instructions to flemoksin soljutab describes the following contraindications to its use:
- hypersensitivity to penicillins and cephalosporins,
- leukemoid reaction lymph type
- infectious mononucleosis.
Before the drug may cause certain side effects, which they say, and reviews of flemoksin soljutab from patients. This effects such as:
- from the gastro-intestinal system: diarrhea, vomiting, nausea, itching in the anus, antibiotic colitis,
- Skin: itching, rash,
- from the kidney: interstitial nephritis,
- very rarely have severe allergic reactions: Stevens - Johnson syndrome, erythema multiforme, toxic epidermal necrolysis.
In patients with severe allergic disorders in history there is a high risk of anaphylaxis while taking the drug Flemoksin soljutab.
Patients with infectious mononucleosis, while taking this drug rash occurs that is not related with hypersensitivity to the drug. Such episodes in history are not a contraindication to the use of flemoksin soljutab.
In appointing the drug Flemoksin soljutab and analogues must take into account the presence of cross-hypersensitivity between cephalosporins and penicillin drugs.
When receiving a high dose of the drug is necessary to pay attention to the use of large amounts of water to prevent crystalluria.
Storage conditions of the drug
According to the instructions Flemoksin soljutab should be stored at room temperature out of reach of children.
Application flemoksin soljutab during pregnancy
The use of this drug during pregnancy is possible, but should take place under the strict supervision of the attending physician, and only for its intended purpose.
Flemoksin soljutab: analogues
Pharmacies occur following analogues flemoksin soljutab: Amoksisara, Amoxicillin, Amosis, Gonoform, Gramoks-D Gryunamoks, Danemoks, Ospamoks, Hikontsil, Ekobol.
Flemoksin soljutab: reviews of preparation
Due to the high efficacy, broad-spectrum, the possibility of appointing in different clinical situations practitioners give very good reviews about flemoksin soljutab. The efficacy demonstrated in several clinical trials. Microbial resistance to the active substance is low. Reviews flemoksin soljutab by patients also talk about its effectiveness, and the release form is very easy to use, including in pediatric practice.
Before using the drug to study in detail the instructions in the flemoksin soljutab, pay special attention to contraindications. Most negative reviews of flemoksin soljutab connected with the failure to comply with recommendations for use, resulting in a significantly increased risk of side effects.