Fenigidin - a calcium channel blocker.
The composition and the form of fenigidin
in the form of coated tablets. One tablet contains the active ingredient - 10 mg of nifedipine.
The package of 40 or 50 tablets.
The drug - a representative of calcium antagonists. Application fenigidin has hypotensive and antianginal effects. Calcium channel blocking prevents entry of calcium ions into the cells of cardiomyocytes and smooth muscle of arterial channels.
According to the instructions fenigidin expands peripheral and coronary vessels, reducing myocardial oxygen demand, it has negative inotropic effects, reduces blood pressure, systemic vascular resistance and cardiac afterload.
In chronic heart failure fenigidin, reviews, improves heart function and reduces its size, inhibits platelet aggregation. Atherosclerosis poststenotic improves circulation, has anti-atherogenic properties.
According to the instructions fenigidin shown in the following cases:
- Raynaud's disease;
- arterial hypertension;
- pulmonary hypertension;
- preventing hypertensive crises;
- bronchial obstruction;
- Hypertrophic cardiomyopathy (including obstructive);
- prevention of angina attacks (including Prinzmetal angina).
The instructions to fenigidin contain the following contraindications:
- severe aortic stenosis;
- pregnancy and breastfeeding;
- hypersensitivity to nifedipine;
- acute phase of myocardial infarction (the first eight days);
- severe hypotension;
- cardiogenic shock;
- heart failure decompensation.
Dosing and dosing regimen fenigidin
Fenigidin of instructions are inside during or after eating.
Individual dosing regimen, depending on tolerability and indications for the drug.
The initial dosage is generally one tablet twice a day. If necessary, the dosage is increased to two tablets per reception. The maximum daily dose is 12 tablets. The duration of treatment on average one to two months.
angina pectoris and for the relief of hypertensive crisis sublingual drug use. To speed up the effect of one tablet fenigidin chewed and kept under the tongue until it dissolves. Thus the patient needs an hour in a prone position. If necessary, a half hour later the drug can be repeated. After cupping of an attack, you can continue on oral administration.
Abolition of the drug carried out gradually.
Side effects fenigidin
In the opinion of fenigidin well tolerated by patients. Quite often, there may be redness of the face and upper body, as well as headache, caused by the decrease of the tone of the cerebral vessels of the brain and their tension by increasing blood flow of arteriovenous anastomoses. In this case it is necessary to reduce the dosage or to take it after a meal.
There were also reviews of fenigidin showing side effects such as drowsiness, dizziness, nausea, hypotension, edema of the lower extremities, palpitations.
In patients with stable angina in the early stages of treatment may experience severe angina pain, and in unstable angina and cardiosclerosis fenigidin may lead to aggravation of myocardial ischemia.
Overdose fenigidin cause the following symptoms:
- severe bradycardia;
- slowing down the conduction;
If symptoms of overdose must enter norepinephrine, intravenous calcium gluconate or calcium chloride solution of atropine.
The preparation is stored in a dark, dry place at room temperature for no longer than two years.