Felodip is a calcium channel blocker, has hypotensive and antianginal effects. The drug normalizes
blood pressure and improves circulation.
Positive feedback Felodip has as an effective drug for the treatment of cardiovascular diseases.
Structure and Composition
The main active ingredient - 2 felodipine 5-10 mg.
Auxiliary components: lactose monohydrate, povidone, hypromellose, magnesium stearate, anhydrous silicon, propyl gallate.
Felodip available in tablets of 2, 5 or 10 mg film-coated. The composition of each tablet shell includes yellow iron oxide, titanium dioxide, talc, red iron oxide, propylene.
Pharmacological action Felodipa
Felodip not have inotropic effects, it reduces the likelihood of myocardial infarction and normalizes blood flow and has anti-ischemic effect. The decrease in blood pressure occurs by reducing vascular resistance. Felodip has a diuretic and antispasmodic action.
The drug reaches maximum concentration in blood plasma for 20-24 hours. It gradually and uniformly distributed in the body, it is absorbed in the gastro-intestinal tract. The therapeutic effect is evident within 3-6 hours after administration and lasted for one day.
Felodip form inactive metabolites in the liver within 25-30 hours. Absorbability of the drug is not dependent on the age of the patient, as well as the functioning of the liver and kidneys. Felodip excreted in urine and feces.
Good reviews Felodip received as an effective drug that increases the elasticity of blood vessels, normalizes blood circulation in the coronary arteries and reduces the risk of disease states. The drug does not cause orthostatic hypotension and renal blood flow increases.
Felodipine, Plendil and Felogeksal are analogues Felodipa. The drug has a similar pharmacological effect, and are used to treat hypertension and circulatory disorders.
Felodip indicated for use in hypertension, angina pectoris, arrhythmias, coronary heart disease, circulatory disorders, Raynaud's syndrome.
Instructions for use Felodipa
In accordance with the instruction
Felodip need to ingest 5 mg 1 time a day, washed down with copious amounts of water. Maintenance dose is 10 mg per day. On the recommendation of the attending physician for elderly patients, the dosage may be reduced to 2 5 mg per day.
When angina should be 5-10 mg 1 time a day. The maximum daily dose of the drug should not exceed 20 mg.
The period of treatment is necessary to constantly monitor blood pressure and blood glucose concentration. Simultaneous administration of flecainide Felodipa and increases the risk of adverse reactions.
According to the instructions Felodip can appoint up to 18 years. The drug can reduce psychomotor reaction, therefore patients to drive a vehicle, you should limit your activities.
Felodip contraindicated in hypersensitivity and hypersensitive to the components of the drug, hypotension, bradycardia, aortic stenosis, pregnancy and lactation, at the age of 18 years.
With care prescribe a drug to patients with hepatic and renal failure, mitral stenosis and acute myocardial infarction.
Side effects Felodipa
Felodip may cause the following side effects:
- on the part of the cardiovascular system - a sharp drop in blood pressure, angina, vasodilation, arrhythmia;
- the central nervous system - headache, dizziness, loss of consciousness, drowsiness, anxiety, tremors, ataxia, depression, fatigue, loss of coordination;
- on the part of the digestive system - vomiting, nausea, diarrhea, dyspepsia, constipation, flatulence, hepatitis, eating disorders, dysfunction of the liver;
- on the part of the circulatory system - anemia, leukopenia, thrombocytopenia;
- allergic reaction - hives, dermatitis, skin rash, eczema, increased photosensitivity, angioedema.