Febrofid - a drug belonging to the group of non-steroidal anti-inflammatory drugs. Present in such dosage forms such as cream, gel, spray and solution for external use.

Active material  Packing Febrofid
 drug - ketoprofen lysine salt.

Pharmacological action

According to the instructions Febrofid has antiexudative, anti-inflammatory and analgesic effect, providing a local therapeutic effect of lesions of tendons, joints, ligaments, skin, muscles, lymph vessels. When the diagnosis of articular syndrome drug reduces the pain in the joints in motion and at rest, reduces their swelling and morning stiffness.

The active substance Febrofida and analogues of the drug penetrates well into the skin and is metabolized in the liver. Ketoprofen is not cumulate (accumulated) in the tissues: about 80% of the dose of substance is released in the form of metabolites, about 10% - leaves the body in the urine in unchanged form.

Indications Febrofidu

According to the instructions to Febrofidu drug is used topically as an agent for external use in the symptomatic treatment:

  • Myalgia, neuralgia, back pain;
  • Inflammatory and degenerative diseases of the musculoskeletal system (bursitis, arthritis, tendinitis, synovitis, lumbago);
  • Uncomplicated, often sports, injuries: sprains, dislocations, torn tendons and ligaments, post-traumatic pain, bruises;
  • Inflammatory diseases of the veins (periphlebitis, phlebitis), lymph nodes, lymph vessels.


Febrofid and analogues of the drug, has similar pharmacological action, is not recommended for people with hypersensitivity to ketoprofen, acetylsalicylic acid (may cause bronchospasm), as well as other non-steroidal anti-inflammatory drugs (NSAIDs). According to the instructions Febrofidu, the drug is not intended for the treatment of dermatoses, weeping, infected sores, wounds, burns and eczema. The drug is contraindicated for use in the III trimester of pregnancy and during breastfeeding. In I and II trimester use Febrofida advisable only in case of urgent need.

Precautions Febrofid used in patients with severe renal and hepatic insufficiency. Do not allow contact with the eyes and mucous membranes.

Side effects Febrofida

Possible side  Gel Febrofid
 Febrofida actions, in the opinion of patients include flushing of the skin, allergic reactions, photosensitivity, purpura, skin eczema.

Interaction with the drugs Febrofida

The feedback to the Febrofidu often noted the appearance of ulcers and gastrointestinal bleeding when co-administered the drug to corticotropin, ethanol, and other NSAIDs.

Application Febrofida with heparin, oral anticoagulants, cefamandole, thrombolytics, cefoperazone, antiplatelet agents increases the risk of bleeding.

According to the instructions Febrofid reduce the effect of diuretics and antihypertensive drugs.

Purpose Febrofida together with sodium valproate causes undesired platelet aggregation, increases the concentration of nifedipine and verapamil in plasma. With the appropriate correction dose active ingredient of the drug increases the hypoglycemic effect of insulin and oral medications.

Mode of application

For external use applied 2-3 times a day with a thin layer, gently rubbing Febrofid in painful and inflamed areas of the body.

The solution was used to rinse 2-3 times a day for its preparation must be injected into the measuring cup 10 ml and dilute the liquid into 100 mL of potable water.