Eutiroks - a means to compensate for the lack of thyroid hormone.
Pharmacological properties Eutiroksa
According to the instructions Eutiroks is a synthetic analogue of the hormone thyroxine. He makes up for the deficit of hormones in their lack of thyroid gland. When the body a drug in the liver and kidney is converted into triiodothyronine, which is involved in metabolism, regulates the growth and differentiation of tissues. Small doses Eutiroksa has anabolic effects on the metabolism of proteins, fats, average doses accelerate metabolism, growth and development of tissues, enhance the functional activity of the heart and brain, high doses of the drug on the principle of negative feedback slows the formation of thyrotropin-releasing hormone and TSH in the head brain, which reduces the formation of triiodothyronine thyroid gland.
The therapeutic effect of the Eutiroksa develops after 7 - 12 days from the start of the drug, it takes the same amount after drug withdrawal. In the case of reduced functional activity of the thyroid gland reviews Eutiroks has a positive effect after 3 - 5 days of completely diffuse goiter cure is achieved in 3 - 6 months.
From the digestive tract Eutiroks absorbed upper intestine, meal impairs the absorption of the drug. In the blood, almost all of it bound to plasma proteins. The main metabolism occurs in the liver, kidneys, muscles, brain. Funds withdrawn from the body is through the kidneys and bowels.
According to the instructions Eutiroks release tablets of 25, 50, 75, 88, 100, 112, 125, 137 and 150 micrograms.
The drug is used for the correction of reduced thyroid - hypothyroidism, in the treatment of euthyroid goiter diffuse toxic goiter (after achieving euthyroid status), after surgical treatment of cancerous lesions of the thyroid gland as a replacement therapy for the prevention of relapse weeks after removal of the thyroid gland. Using Eutiroksa carry out various function tests.
Do not use the drug in cases of untreated thyrotoxicosis, and adrenal insufficiency, acute inflammatory lesions of the heart (myocarditis, pancarditis), acute myocardial infarction, drug intolerance. Carefully apply it, if the patient has associated arrhythmias, ischemic heart disease, high blood pressure, diabetes, long-existing hypothyroidism.
Instructions for use Eutiroksa
Tablets are intended for reception on an empty stomach (not before 30 minutes before a meal) with water. They can not chew. Depending on the indication eutiroks dose picked individually.
For patients with a significant excess body weight the dose is calculated on for this is meant to increase the weight.
If you need replacement therapy for hypothyroidism, patients under the age of 55 years in the absence of heart disease the recommended dose of 1, 6 - 1, 8 mg / kg / day (the average for women of 75 - 100 mg / day for males 100 - 150 mg / day). If the patient is 55 years or longer has associated heart disease, the daily dose of 0, 9 mg / kg, begin with a dose of 25 mg / day. If necessary, the dosage is increased gradually by 25 mg every 2 months to the normal values of thyroid-stimulating hormone. It requires constant reception Eutiroksa throughout life.
Severe hypothyroidism requires careful assignment Eutiroksa with small doses - 12, 5 mg / day, regularly monitoring TSH.
Congenital hypothyroidism in children younger than 6 months requires the appointment of 25 - 50 mg / day, from 6 to 12 months, 50 - 75 mg / day, from 1 to 5 years 75 - 100 mg / day, from 6 to 12 years 100 - 150 mg / day, 12 years 100 - 200 mg / day. For children the drug is prescribed for 1 admission (in the morning before eating) for life.
In the complex treatment of hyperthyroidism Eutiroksa daily dose of 50 - 100 mcg when cancerous lesions of the thyroid gland 50 - 300 micrograms. The duration of treatment is determined individually.
In the opinion of Eutiroks able occasionally cause allergic reactions. If you strictly follow the dose, the risk of adverse reactions is minimal.