Estrone - belongs to the group of hormones  Packing folliculin
 and their analogues and is a natural hormone ovaries (follicle stimulating hormone).

Pharmacological action

Estrone action has on the body similar to the action of estrogen - produced by the ovaries and adrenal glands of female hormones. Estrogen is responsible for the development of sexual organs and secondary sexual characteristics in women. They contribute to the widening of the (proliferation) of the inner layer of the uterus (the endometrium). Together with progesterone (a hormone of the corpus luteum) are actively involved in the regulation of menstrual function.


According to the instructions estrone used to treat insufficiency yaichnikov.Po reviews estrone and effective for the treatment of certain skin diseases (hypertrichosis - uncharacteristic sex and age increased development of hair, acne, etc.).

Guide to estrone

In primary amenorrhea (menstrual never been) combined with underdeveloped genitals and / or secondary sex characteristics of drug administered in the form of intramuscular injections performed every day or every other day for 10 000-20 000 units for one or two months. After uterine size appreciably increase further assigned Progesterone for 5-6 days by intramuscular injection, 5 mg daily. If necessary, hormone therapy can be continued.

In the opinion of estrone is effective in the treatment of secondary amenorrhea - the cessation of normal menstrual period for more than six months in the absence of pregnancy. In this case, the drug is administered intramuscularly daily to 10 000 units in 15 days, followed by 6-8 days appoint Pregnin or progesterone. In the absence of the effect of hormone therapy carried out, repeat the treatment.

When infertility, hypo -and oligomenoree, whose development is conditioned hypoplasia (underdevelopment) of the uterus and ovaries hypofunction estrone administered immediately after the next menstruation for 15 days intramuscularly 5 000-10 000 IU per day. Beginning 16 days, if necessary, appoint 7-8 days Pregnin or progesterone. Courses of treatment can be repeated if necessary, many times.

According to the instructions estrone can be used to treat pathological manifestations of menopause, is associated not only with the natural aging of the female organism, but also caused by the surgical removal of the ovaries. In this case, every other day intramuscularly administered for 5 000-10 000 IU estrone. A course of treatment is usually given 10 to 15 injections. If the symptoms of the pathological menopause occurs again, the treatment can be povtorit.Pri It should strive to use the minimum dose of the drug to ensure the achievement of the positive effect of the therapy, and be sure to take into account the patient's age, stage of menopause, severity of nervous and cardiovascular disorders.

In the opinion of estrone opens your cervix at term pregnancy. The drug is administered intramuscularly at a dose of 40 000-50 000 units in just a few hours before rodostimuliruyuschih therapy.

Side effects folliculin

Long-term use  The vials folliculin
 the drug can lead to uterine bleeding.


According to the instructions contraindications to estrone are:

  • Malignant neoplasms in women younger than 60 years;
  • Breast;
  • Endometritis;
  • Increased risk of uterine bleeding;
  • Hyperestrogenia phase of menopause, ie, the period during which the emission of female sex hormones increased.

Form release estrone

Estrone is produced in the form of an oily solution, in ampoules of 1, 0 ml (5000 IU). The pack of 6 vials; in ampoules of 1, 0 ml with an active matter content of 10 000 IU, 3 vials per pack.

Synonyms folliculin

Telekinin, Telestrin, Proginon, Estroginon, Estroglandol, Menformon, Ketogidroksiestrin, Ketodestrin, Ginestril, Glandubolin, Femidin, Folestrin, Estruzol, Estrugenon, Kristallovar, estrone.

storage conditions

Estrone refers to the list B. It should be stored in a cool, dark and dry place.