Ersefuril - antidiarrheals, intestinal antiseptic.
Product form preparation - into hard gelatin capsules contained within yellow powder. 1 capsule contains 200 mg ersefuril nifuroxazide and auxiliary ingredients: magnesium stearate (1, 8 mg), sucrose (72 mg), cornstarch (88 mg).
Pharmacological action ersefuril
Therapeutic effect on ersefuril instruction is blocking the activity of dehydrogenase enzymes - substances that give effect to the reactions of lipid, carbohydrate metabolism and oxidation in a microbial cell. Nifuroxazide inhibits the citric acid cycle, respiratory chain, destroying the membrane and prevents the implementation of a number of biochemical processes in the cells, which are the "culprits" of an intestinal infection.
Action ersefuril also is to enhance the immunity of the patient, increasing the titer of complement and phagocytosis - the process in which the absorption of hostile to our body cells by special microorganisms (phagocytes). Application ersefuril therapeutic doses provides a bacteriostatic effect of the drug, at higher doses - bactericidal.
A drug effective against Gram positive (Streptococcus, Staphylococcus, Clostridium) and Gram (Salmonella, Escherichia coli, Shigella, Enterobacter, Klebsiela, Vibrio cholerae) microorganisms.
The feedback to the Ersefurilu not marked negative impact of the drug on saprophytic intestinal flora involved in the formation of immunity - that is, the use of funds does not cause dysbiosis.
Resistant bacterial strains to the drug, according to medical research, does not develop. While infecting organism enterotropnymi viruses ersefuril prevents bacterial superinfection.
According to reviews ersefuril used for acute bacterial diarrhea, effectively restoring eubioz (equilibrium) of the intestinal flora.
Diarrhea (acute diarrhea of bacterial nature). The drug is given in the absence of suspicion of worms infecting organism (invasion). In the case of infectious diarrhea with symptoms suggestive of infestation necessary appointment systematic antibiotic therapy.
Treatment Ersefurilom on the testimony does not negate the need for rehydration process, which refers to the restoration of water-salt metabolism, if required.
Hypersensitivity to derivatives of nitrofuran, children up to 6 years. Use of the drug during pregnancy is possible if indications Ersefurilu - if the anticipated benefits from receiving funds greater than the risk for the full development of the fetus. Do not use prohibited ersefuril lactation.
Due to the presence in the composition of ersefuril sucrose intake of the drug is not recommended to persons suffering from malabsorption syndrome glucose, galactose, fructose intolerance or sucrase-isomaltase deficiency.
Side effects ersefuril
In some cases, the drug can cause an allergic reaction - such as hives, skin rash, angioedema or anaphylaxis.
Optimal storage conditions for ersefuril instructions is dry and cool place at a temperature no higher than 30 degrees Celsius. Shelf life - 5 years. Use the drug after the expiry date is not recommended.