Dyurogezik - narcotic analgesic.  Dyurogezik

Pharmacological action

Dyurogezik has a sedative and analgesic effect, it is considered psychotropic and narcotic drugs.

It was also noted that increases the threshold of pain Dyurogezik: prevents the transmission of pain excitation pathways to the amygdala, hypothalamus, thalamus nuclei, slow heart rate, stimulates the vomiting center and depresses the respiratory center, increases the tone of the sphincter muscle, bile ducts, reduces peristalsis, increases the level of water absorption from the gastrointestinal tract, reduces renal blood flow, causes euphoria and helps sleep. In the blood pressure Dyurogezik no effect.

The active substance Dyurogezika - fentanyl.

Product form

Release patch Dyurogezik, solution for injections.

Indications Dyurogezika

Dyurogezik for injection are used during moderate to severe pain syndrome, developing myocardial, angina, cancer pathology, trauma, after surgery, for sedation in different types of anesthesia, combined it with droperidol, for neuroleptanalgesia.

Plaster Dyurogezik effective for chronic pain of moderate to severe severity occurring in cancer, arthritis, neuropathy, herpes zoster or varicella and other diseases.

Instructions Dyurogezika: methods of use

In preparation for operations Dyurogezik administered intravenously at a dose of 0, 05-0, 1 mg with 2 5-5mg droperidol.

To perform general anesthesia is administered the drug intravenously - 0, 4-0, 6 mg for the maintenance of anesthesia - IV 0, 05-0, 2 mg every 20-30mg. For pain relief after surgery is administered intramuscularly Dyurogezik - 0, 05-0, 1 mg.

To eliminate the pain associated with myocardial administered 0, 1 mg to 5 mg of the drug droperidol for three minutes.

Children in preparation for the operation introduced 2mkg / kg Dyurogezika, for general anesthesia - intravenous 10-150mgk / kg or 150-250mkg / kg intramuscularly. To maintain anesthesia is administered to children 1-2mkg / kg intravenously or 2mkg / kg intramuscularly.

Adhesive is applied topically Dyurogezik: 72 hours is applied to the skin in which no irritation or minimal amount of hair. If necessary, you can wash the skin, but without the use of detergent, and then dry well.

 Plaster Dyurogezik
 Patients who did not previously opiates prescribed in Dyurogezik starting dose 25mkg / h. If the patient is tolerant to opiates, Dyurogezika dosage is calculated individually.

side effects

Dyurogezik can cause respiratory depression, central nervous system, onlivost, headache, convulsions, delirium, diplopia, blurred vision, loss of memory, unusual dreams, confusion, hallucinations, euphoria, increased intracranial pressure, vomiting, flatulence, nausea, spasm of the sphincter of Oddi , constipation, biliary colic, bradycardia, pressure reduction, suppression of cardiovascular activity, urinary retention, ureter spasms, fever, itchy skin, bronchospasm, laryngospasm, increased sweating, dependence and withdrawal syndrome, accompanied by nervousness, irritability, nausea, diarrhea, vomiting, anorexia, trembling, dilated pupils, general weakness, vague pain, rhinitis, palpitations.

If overdose occurs Dyurogezika nervousness, decrease in pressure, drowsiness, weakness, dizziness, bradycardia, depression of the respiratory center, clammy sweat, sleep apnea, and pupillary constriction. For the treatment of naloxone administered, if necessary - muscle relaxants, atropine, conduct artificial respiration, blood volume fill.

Side effects of the patch Dyurogezik

Application of the plaster may cause redness, rashes, itching, burning.


Dyurogezik can not be taken for severe depression of the respiratory center, hypersensitivity.

The patch can not be imposed for removal and postoperative acute pain on irritated, damaged or exposed skin, diarrhea caused by colitis, formed due to receive penicillins, cephalosporins, lincosamides, with toxic dyspepsia, acute respiratory depression. You also can not be used for pain relief patch Dyurogezik nursing, pregnant women, children up to 18L.

Be wary appoint Dyurogezik with hepatic / renal failure, hypotension, acute diseases of the peritoneum, cesarean section and other obstetric operations, respiratory failure, traumatic brain injury, in tumors of the brain, kidney or liver colic, hypothyroidism, cholelithiasis, with generally serious condition, alcoholism, benign prostatic hypertrophy, hyperthermia, suicidal tendencies, while the appointment of glucocorticoids, insulin, drugs lowering pressure, MAO inhibitors.

Injections Dyurogezik prescribed with caution in elderly patients, nursing, pregnant women, children.

The patient is warned that the active ingredient inhibits Dyurogezika psychomotor reaction and affects the concentration.

The likelihood of side effects increases Dyurogezika combination with hypnotics and sedatives, phenothiazines, drugs for general anesthesia, peripheral muscle relaxants, ethanol, tricyclic antidepressants, opiates, antihistamines drugs, provide additional sedation.

Dyurogezik enhances the effect of the pressure reduction means.

Reduce the dose of fentanyl while his appointment with antihypertensive drugs, corticosteroids, insulin.