Dufalak - synthetic laxatives used to restore the functions of the intestine, chronic constipation and reduce the formation of toxins in the liver failure.

Pharmacological action

The active substance Dufalaka - lactulose, which is synthesized from lactose dairy products.

The large intestine falls unchanged, where it interacts with the intestinal flora. Digested in the large intestine in the organic acids stimulate peristalsis, eliminating constipation, and restores the physiological rhythm of bowel movements. It enhances the growth of lactobacilli and bifidobacteria and suppress the growth of pathogenic bacteria (Escherichia coli, Clostridium), which helps to improve the balance of intestinal flora. Improves the absorption of calcium and phosphate, inhibits the growth of Salmonella. By reducing the content of ammonia in the blood is used in the treatment of liver failure. Widely used in pediatrics.

Product form

Dufalak discharged as a clear, colorless viscous syrup. 100 ml of the preparation containing 66, 7 g of lactulose and purified water as an excipient.

The disposable bags of 15 ml, 10 bags in a carton; in plastic bottles of 200 ml, 500 ml, 1000 ml with measured glass included.

Indications Dufalaka

Dufalak used for:

  • Hepatic encephalopathy;
  • Intestinal dysbiosis;
  • Putrid dispersion syndrome after acute food poisoning in children;
  • Enteritis caused by salmonella;
  • Constipation: to regulate the physiological rhythm of emptying the colon; to soften the stool to carry out operations in the area of ​​the anus or colon, or with hemorrhoids.


According to the instructions Dufalak is contraindicated in:

  • Bowel obstruction;
  • Hypersensitivity to the drug;
  • Metabolic disorders in the conversion of galactose to glucose (galactosemia).

Precautions Dufalak used for:

  • Diabetes;
  • Lactose intolerance;
  • Hepatic precoma;
  • Undiagnosed rectal bleeding.

Instructions for use Dufalaka

 Duphalac syrup
 According to the instructions Dufalak taken orally morning while eating in diluted or undiluted form. The dose can be divided into 2 doses.

In the treatment of constipation and for softening stools in medical applications Dufalak used:

  • Adults - 15-45 ml maintenance dose - 15-30 ml;
  • Children from 7 to 14 years - 15 ml, the maintenance dose - 10-15 ml;
  • Children from 1 to 6 years to designate the starting and maintenance dose - 5.10 ml;
  • Dufalak for newborns under one year are used in the amount of 5 ml for the initial and maintenance dose. During treatment, a drug may cause disorders reflex emptying.

The effect of reviews on Dufalaka usually occurs within 2 days. Therefore, the dose can be reduced. If no improvement, then increase the dose or frequency of administration.

In the treatment of salmonellosis and shigellosis first 10-12 days of use 15 ml 3 times per day. After a seven-day break follows, without changing a single dose, to increase the number of receptions to 5 times per day.

In the treatment of hepatic coma and precoma starting dose is 30-45 ml 3 times a day. Then the dose individually and reviewing selected for a soft chair was 2-3 times a day. In severe cases, the drug is prescribed in the form of an enema, for which it is diluted to 300 ml per 700 ml of water.

Dufalak for newborns up to 1 year in the treatment of intestinal dysbiosis appoint 1, 5-3 ml per day. For children up to 3 years, the dose is 3 ml, 4 to 7 years - 5 ml, over 7 years and adults - 10 ml.

side effects

In the opinion of Dufalak well tolerated and adults, and children.

In the early days it may cause flatulence, which usually takes a few days. They may also experience nausea, abdominal pain or vomiting. When using Dufalaka in high doses can cause diarrhea and electrolyte imbalance.

In case of overdose can cause diarrhea and abdominal pain.

Dufalaka data on the interaction with other drugs is not.

Safe drug for the treatment of constipation in diabetes and did not require any additional adjustments.

Dufalak can be used if indicated during pregnancy and lactation.

storage conditions

Dufalak can be purchased without a prescription.

Shelf life - 3 years.