Diphenhydramine ampoules
 Diphenhydramine - antihistamine.

Pharmacological action

Diphenhydramine has anti-allergic, anti-emetic, hypnotic, mestnoanesterziruyuschim, antispasmodic, sedative effect.

The drug reduces, prevents spasms of smooth muscles, increased capillary permeability, tissue swelling, congestion and itching caused by histamine.

There was widespread in medical practice has received dipyrone combination with diphenhydramine.

Product form

Produce a drug in powder form, tablets, suppositories, sticks, gel sticks. Diphenhydramine is also releasing a solution in ampoules.

Indications diphenhydramine

Diphenhydramine is indicated for hay fever, vasomotor rhinitis, itching dermatoses, urticaria, acute iridocyclitis, conjunctivitis allergic, swelling angionevroticheskih, kapillyarotoksikoz, serum sickness, allergic complications of drug therapies, blood transfusions and fluids, its replacement.

Diphenhydramine is effective in the treatment of radiation sickness, anaphylactic shock, bronchial asthma, gastric ulcer, gastritis hyperacid, for colds, sleep disorders, extensive soft tissue injuries, skin sedation, chorea, Parkinson's disease, air, sea sickness, Meniere's syndrome, the holding of local anesthesia in patients who have in the past been observed allergic reactions to other local anesthetics.

mode of application

 Diphenhydramine Tablets
 Inside designate an adult to take diphenhydramine, one to three p / day 30-50mg. Treatment lasts 10-15dn. For insomnia take 50mg for about half an hour before bedtime. If motion sickness is recommended every 4-6ch. take 25-50mg.

Diphenhydramine children 2-6l. appoint 12 5-25mg; 6-12l. - 25-50mg every 6-8ch.

Intramuscular injections are administered in the amount of diphenhydramine 50-250mg. Drip administered diphenhydramine 20-50mg.

Diphenhydramine is also prescribed to children in the form of rectal suppositories. Children up to three years - 5 mg, 3-4g. - 10mg; 5-7l. - 15mg; 8-14l. - 20mg.

Also make shots diphenhydramine, combining it with other drugs that increase its effect. For example, injections Analgin with diphenhydramine and papaverine are effective for removing heat. For adults and children after 14L. combined in one vial syringe diphenhydramine, Analgin, papaverine.

side effects

Diphenhydramine may cause negative reactions on the part of such systems:

  • sense organs, the nervous system: fatigue, decreased attention, weakness, drowsiness, headache, incoordination, dizziness, irritability, anxiety, nervousness, euphoria, irritability, paresthesia, diplopia, tinnitus, blurred vision, convulsions, optic neuritis, tremor , acute labyrinthitis, confusion;
  • cardiovascular and hematopoietic systems: tachycardia, hypotension, thrombocytopenia, palpitations, arrythmia, agranulocytosis, hemolytic anemia;
  • GI: anorexia, vomiting, dry mouth, numbness of the mouth is short, epigastric distress, constipation, diarrhea, nausea;
  • Respiratory: thickening of bronchial secretions, dry throat, nose, shortness of breath, tightness in chest, stuffy nose;

Diphenhydramine is also in ampoules (injections), tablets, and other dosage forms can cause allergic reactions, sweating, photosensitivity, chills.

Contraindications specified in the instructions to diphenhydramine

Diphenhydramine is contraindicated during lactation, newborns, premature babies, with hypersensitivity-closure glaucoma, prostatic hypertrophy of the prostate, bladder neck stenosis, obstruction pyloroduodenal, stenosing gastric ulcer, duodenal ulcer, bronchial asthma during pregnancy.