Diflazon - antifungal agent.


Pharmacological action Diflazon

The active substance Diflazon - fluconazole, which inhibits the fungus Candida, Cryptococcus, microspores, Trichophyton, blastomycosis, coccidioidomycosis pathogen, histoplasmosis.

Product form

Producing a solution, tablet, syrup, powder, capsule Diflazon.

Analogs Diflazon: Diflyuzol, Diflucan, mikomaks, Medoflyukon, Mikosist, Mikoflyukan, Nofung, Flukozid, Fluconazole, Flukozan, Fluzole.

Indications Diflazon

Diflazon used for skin infections and pulmonary sepsis, meningitis, and other systemic lesions Cryptococcus, for the prevention of infection in those who are sick with AIDS.

Helps Diflazon when candidemia, candidiasis that struck the peritoneum organs, respiratory, genitourinary system, eyes, endocarditis, including in those patients who undergo immunosuppressive or cytotoxic therapy.

The instructions Diflazon indicated that the drug can be prescribed for the treatment of mucosal candidiasis of the esophagus, throat, mouth, bronchus, lung, oral candidiasis atrophic provoked wearing dentures, mucocutaneous candidiasis, mycosis groin, body, feet, onychomycosis, pityriasis lichen, Candida skin infections, sporotrichosis, histoplasmosis, coccidioidomycosis, and (if the normal immune system).

There are reviews of Diflazon successfully used for the treatment of genital candidiasis or vaginal balanitis acute and chronic.

Diflazon used for the prevention of fungus on the face of radiation or chemotherapy, for the prevention of recurrence of oropharyngeal candidiasis in AIDS patients.

Instructions Diflazon: how to use

In cryptococcal infections, disseminated candidiasis, candidemia take in 1 day and then 400mg Diflazon 200-400mg one p / day.

To prevent cryptococcal meningitis AIDS prescribe 200mg / day.

For the treatment of oropharyngeal candidiasis take over 7-10dn. 50-100mg one row / day. To prevent this form of candidiasis AIDS patients prescribed one 150mg p / week.

In oral atrophic candidiasis, caused by wearing dentures take 50mg Diflazon one p / day for two weeks, combining the drug with antiseptics for dentures.

In other forms of mucosal candidiasis (except genital candidiasis) take 50-100mg / day. for 14-30 days.

When vaginal candidiasis take vnutr150mg Diflazon once. To prevent relapses take one 150mg p / month. for 4-12 months.

When balanitis, which provoked fungi Candida taking 150mg once.

For the prevention of candidiasis it is recommended to take Diflazon 50-400mg per day.

If the risk of generalized infection increased, it is possible to take 400mg / day.

When fungal infections of the skin, including in the groin, tinea pedis, candidiasis take one 150mg Diflazon p / week or one 50 mg p / day. The treatment lasts for 2-4 weeks and up to 6 weeks. at the athlete's foot.

When herpes otrubevidnom take one 300mg p / wk. for 2 weeks or 50 mg 1 p / day for 2-4 weeks.

For the treatment of onychomycosis are taking 150mg Diflazon one p / week to a complete change of the infected nail.

In deep endemic mycosis take 200-400mg / day. Treatment lasts 2-17 months paracoccidioidomycosis., 3-17 months. if histoplasmosis, 11-24 months. coccidioidomycosis, 1-16 months. when sporotrichosis.

Babies Diflazon appoint a special dosage form for children, give medication one p / day.

When candidiasis that struck the esophagus, mucous children are given 3 mg / kg / day for three weeks; generalized candidiasis and cryptococcal infections - 6-12mg / kg / day of 10-12 weeks.

To prevent the development of fungal infection to children who have lowered immunity, against the background of radiotherapy or chemotherapy developed neutropenia appoint 3-12mg / kg / day.

Children who disrupt the function of kidneys Diflazon daily dosage is reduced.

 Diflucan - analogue Diflazon
 Judging by the reviews of Diflazon, in elderly patients if the kidney function is not broken, you can take the drug at the standard scheme.

Despite the similarity of the principle of action to be taken Diflazon counterparts, first studying their instructions.

side effects

Diflazon can cause nausea, diarrhea, dental pain, appetite loss, abdominal pain, constipation, flatulence, abnormal liver function, kidney, dizziness, fatigue, cramps, headache, thrombocytopenia, agranulocytosis, leukopenia, neutropenia, skin rash, erythema multiforme exudative, toxic epidermal necrolysis.

There are reviews of Diflazon, causing hair loss, hypokalemia.

If overdose occurs paranoia, hallucinations. For the treatment of poisoning washed stomach, conducted forced diuresis.


Diflazon of instruction is contraindicated in case of hypersensitivity. With care prescribe a drug for kidney, liver failure, alcoholism, during lactation, pregnant women, children up to six months.

Do not take Diflazon Diflazon and analogues with the same active substance together with hepatotoxic drugs.