Clione, etc.

 Clione 100-d
 Clione, etc. - combined with a synthetic drug antifungal, antibacterial and antiprotozoal effect, used in gynecology.

Pharmacological action

Active ingredients Klion-d have protivoprotozoynyoe, antibacterial and antifungal activity.

The drug is active against:

  • Giardia lamblia;
  • Fusobacterium spp .;
  • Prevotella spp .;
  • Eubacterium spp .;
  • Gardnerella vaginalis;
  • Peptostreptococcus spp .;
  • Bacteroides spp .;
  • Peptococcus spp .;
  • Entamoeba histolytica;
  • Trichomonas vaginalis;
  • Clostridium spp .;

Also Klion-d has antifungal activity against dermatophytes and yeasts, mainly against Candida albicans.

In the opinion of Clione-d is well tolerated and does not change the composition of normal microflora and acidity of the vagina.

Product form

Clione, etc. produced in the form:

  • Tablets, each tablet contains 250 mg of metronidazole for 20 tablets in the pack;
  • Infusion solution in a bottle of 100 ml;
  • Oval biconvex vaginal tablets with a pointed end and engraved "100" (candle-Clione Clione or e-d 100), each tablet contains 100 mg of metronidazole and miconazole nitrate. 10 candles in the package.

Indications Klion-d

According to the instructions of Clione-d is used to treat infectious and inflammatory diseases caused by fuzobakterii, clostridia, bacteroides and anaerobic cocci:

  • Abscesses in the pelvic area;
  • Sepsis;
  • Osteomyelitis;
  • Endometritis;
  • Gas gangrene;
  • Peritonitis;
  • Meningitis.

Also Klion-d is used as prevention of postoperative infectious complications that can cause anaerobic flora - bacteroides and anaerobic streptococci, especially after operations on the pelvic and abdominal cavity.

Clione 100-d is used as a topical treatment of vaginitis of mixed etiology, which simultaneously causes Trichomonas spp. and Candida spp.


According to the instructions of Clione d'contraindicated in:

  • Leukopenia;
  • Hepatic Insufficiency;
  • Hypersensitivity to the Klion e-azoles and other;
  • Organic lesions of the central nervous system, including epilepsy.

Clione-D during pregnancy in the first and second trimesters, in children under 12 years old and lactation is contraindicated in any dosage forms.

According to the instructions of Clione d'prescribed with caution in disorders of microcirculation and diabetes. When using e-Klion should not drink alcohol.

Instructions for use Klion-d

 Clione pills
 According to the instructions of Clione-d in the form of tablets taken:

  • When trihomonadozah - one twice a day, morning and evening, for 10 days. Perhaps the use of 8 tablets as a single dose in the evening;
  • When lambliozah - for a week, 2 times a day 2 tablets;
  • When amoebiasis - three times a day, 2 tablets for 7-10 days.

The infusion solution is used intravenously and drip rate of 7 days. While improving the state of the switch to oral Klion-d 3 times a day 400 mg.

Candles Klion d'applied vaginally after moistening the tablet with water. Usually treatment Klion-d 100 lasts 10 days with simultaneous oral administration of drugs containing metronidazole (Clione, etc.).

During the period of candles Klion e-advised to refrain from sexual intercourse. It is also recommended that the simultaneous treatment of the sexual partner Klion-d ingestible matter whether he has manifest disease.

When pregnancy Klion d'licensed for use only on strict conditions in the third trimester. Typically, the drug is prescribed for vaginal candidiasis (thrush).

In the opinion of Clione-d during pregnancy is most safe and effective when applied to the 36-37 week.

side effects

When using e-Klion 100 for instructions can result in various side effects - itching, pain, irritation and burning of the vaginal mucosa. The use of candles Klion-d can also cause white, thick mucous vaginal discharge without odor and a burning sensation or irritation of the penis in a partner.

In the opinion of Clione-d when taken orally can cause vomiting, loss of appetite, nausea, headache, altered taste, dizziness, metallic taste in the mouth, constipation, abdominal pain and diarrhea.

Allergic reactions such as itching, rashes and urticaria Klion e-Review is rare.

storage conditions

Clione d'released under doctor's prescription. The shelf life of the drug - 5 years.