Cinnarizine - a drug used primarily to treat various disorders of cerebral circulation.

Pharmacological action

Cinnarizine reduces the content of calcium ions in the cells, relaxes the muscles of the arterioles, as well as enhances the vasodilatory action of carbon dioxide.  Cinnarizine in the package

This drug not only affects the state of the tone of the vascular wall, but also reduces the vascular response to dopamine, angiotensin, epinephrine, norepinephrine and vasopressin.

Application cinnarizine enhances the lumen of blood vessels, including the brain. There were no blood pressure lowering.

In addition, the drug reduces the excitability of the vestibular apparatus to suppress nystagmus, lowers the tone of the sympathetic nervous system, increases the resistance of tissues to hypoxia and reduces blood viscosity.

Cinnarizine also has an average antihistaminic activity.

The drug is rapidly absorbed from the digestive tract, and by 91% bound to plasma proteins. Its maximum concentration in blood after 2 - 3 hours after dosing.

No teratogenic.

Product form

Cinnarizine release tablets, each containing 25 mg of active substance per pack of 50 cards in the form of droplets in bottles of 20, 0 ml, containing 75 mg of cinnarizine.

Analogues of this drug are stugeron, Tsinnaron, Tsinedil, Vertizin.

Indications Cinnarizinum

This drug is widely used in medical practice. Indications Cinnarizinum following:

  • Various circulatory disorders in the brain (atherosclerosis, ischemic stroke, after suffering traumatic brain injury and hemorrhagic stroke, encephalopathy);
  • Nausea, vomiting and tinnitus labyrinth of origin;
  • Meniere's disease;
  • Nystagmus;
  • Thought disorders;
  • The decline and memory loss;
  • Senile dementia;
  • Inability to concentrate;
  • Peripheral circulatory disorders (thrombophlebitis, Raynaud's disease, diabetic angiopathy, trophic ulcers, a syndrome of "intermittent" claudication);
  • Prophylaxis of migraine;
  • Prevention kinetoses (sea and air sickness).

Another indication for cinnarizine is symptomatic therapy of cerebrovascular pathologies that manifest bouts of dizziness, headaches, irritability, tinnitus.

Instructions Cinnarizinum - method of application

At disturbances of cerebral blood flow administered three to six tablets daily.  Cinnarizine Tablets

At various disorders of peripheral blood circulation is assigned from 150 to 225 mg per day Cinnarizine, ie six to nine tablets.

When the vestibular disorders instruction Cinnarizinum recommends taking it to three tablets a day.

In the opinion of Cinnarizine it is a good tool for the prevention of motion sickness. 30 minutes before departure, journey or the flight should take one tablet (25 mg). If need be, that after 6 hours the dose may be repeated once more. Babies to give half of the adult dose.

If the patient is not very well tolerated Cinnarizine, he begin treatment with half the dose and gradually increase it until the therapeutic.

Side effects Cinnarizinum

According to the instructions Cinnarizine may have the following side effects:

  • Headache;
  • Drowsiness;
  • Depression;
  • Extrapyramidal disorders;
  • Fatigue;
  • Dry mouth;
  • Epigastric pain;
  • Cholestatic jaundice;
  • Dyspepsia;
  • Weight gain;
  • Skin rash;
  • Allergic reactions.

In the opinion of Cinnarizine rarely can lead to limb tremor and improve muscle tone.

Contraindications to the Cinnarizine

According to the instructions Tsinnarizinprotivopokazan case of hypersensitivity to the drug and nursing mothers.

With caution the drug must be administered to people suffering from Parkinson's disease.

In pregnancy, the indications for use of cinnarizine should be very carefully evaluated by your doctor. Although repeatedly conducted tests teratogenic effect of the drug has not been proven, it is still recommended to use only if the anticipated benefits of therapy outweighs the potential risk.


Cinnarizine enhances the action of vasodilators, antihypertensives, sedatives and alcohol. Reduces the effectiveness of drugs to treat hypotension.

In the opinion of Cinnarizine significantly increases the efficiency of both used him nootropnyhlekarstvennyh drugs.


In case of accidental or deliberate decision into a large dose Cinnarizinum performed gastric lavage and give activated charcoal. Further treatment is symptomatic, because No specific antidote.


By instruktsiiTsinnarizindolzhen wary appoint drivers and others whose jobs require high concentration of attention, because at the beginning of the treatment is often marked drowsiness.

With prolonged use of cinnarizine is necessary to control the picture of peripheral blood, kidney and liver function.

In appointing the drug athletes must consider that it has an impact on the results of doping control.

Storage conditions Cinnarizinum

Tsinnarizinotnositsya to the list B. It was stored at room temperature, protected from light.