Pharmacological action


Betadine is an antiseptic for topical use, which is a combination of iodine and its binding polyvinylpyrrolidone.

The complex of these substances called povidone-iodine, also sounds and the international non-proprietary name Betadine. This drug has a bactericidal, antiseptic, antiviral, antiprotozoal (affects protozoa), antifungal and disinfectant action. Iodine, which is part of Betadine, in contact with skin or mucous membranes is released from the complex with polyvinylpyrrolidone and damages the cells of pathogenic microorganisms. The drug takes effect within 15-30 seconds after application, and for 1 minute there is a complete death of microorganisms. The effectiveness of Betadine iodine color shows that after exposure to microbes, fungi, protozoa and viruses begin to weaken.

Long-term topical application of Betadine causes significant absorption of iodine, especially when handling large wound surfaces, however, after the last administration of the drug for 1-2 weeks, the concentration of iodine in the blood is returned to the initial indicator. Clinical studies and Betadine ratings indicate that the drug lasts longer than conventional iodine alcohol solution, and non-irritating action.


Betadine is available in the form of an aerosol concentrate for solution, ointment, suppository, and the solution, each form has its own indications.

Betadine ointment is administered in the following cases:

  • prevention of infection with small bruises, cuts, burns, minor surgical interventions;
  • treatment of infected bedsores or venous ulcers;
  • treatment of fungal, bacterial and mixed infections of skin.

According to the instructions betadine, the drug as a solution used for:

  • antiseptic treatment of burns;
  • antiseptic treatment of mucous membranes or skin prior to procedures and operations;
  • hygienic and surgical hand disinfection;
  • bladder catheterization, holding punctures, injections, biopsies;
  • contamination of mucous membranes or skin infected material as a first aid.

Betadine candles should be used when:

  • acute and chronic vaginal infections: bacterial vaginosis, genital herpes, trichomonas infection, and others;
  • as part of combination therapy for trichomoniasis;
  • processing related diagnostic and obstetrical procedures, as well as transvaginal surgical procedures;
  • vaginal yeast infections, which were provoked by anti-bacterial therapy, and steroid medicines.

Instructions for use Betadine

Betadine ointment is used topically. Before applying the product wound surface should be clean and dry. Betadine ointment is applied in a thin layer, then it is possible to impose aseptic bandage. Infectious wounds treated 1-2 times a day for two weeks. To prevent contamination when Betadine ointment usually use one every three days until it is time until the desired effect is achieved.

Betadine solution can be used undiluted or diluted with water as follows:

  • for handling small abrasions, wounds, burns using a concentrated solution of 10%;
  • pustular diseases of the skin and acne, according to the instructions Betadine, wiped swab with concentrated 10% or 5% (1 part of the solution, and 2 parts water) solution;
  • disinfection of healthy skin to various medical procedures (taking of blood, puncture, infusion, biopsy, transfusion) is performed using a concentrated solution for 1-2 minutes;
  • disinfection of mucous membranes and skin before surgery using Betadine solution for two minutes, twice; wiping the patient before the operation is performed with a sponge soaked in 0, 1% - 0 05% solution, which is obtained by diluting one part of 10% solution of 100 parts of water and 200 respectively;
  • effects of invasive procedures are treated with 10% or 5% solution;
  • Aseptic conducting healing and treatment of complications was 5% solution or undiluted;
  • treatment of burns can be made 10%, 5% or 1% (1 part Betadine and 10 parts of water) solution, depending on the state of the burn surface;
  • washing the joint cavity and serous cavities - 1% - 0, 1% solution;
  • in ophthalmology and Transplantation - 1% - 5% solution;
  • the surgical treatment of cysts of parenchymal organs, during small gynecological operations, for the treatment of genital tract applies a concentrated solution of Betadine;
  • skin treating newborns using 0 1% solution, umbilical wound - 10% solution, and for the prevention of conjunctivitis in infants - 2-3 drops in the eyes 2, 5% - 5% solution;
  • for bacterial or fungal dermatitis - 1% solution;
  •  Betadine candles
  • papillomavirus and herpes on the skin treated with a concentrated solution of Betadine.

Betadine candle, which should be a little bit wet. It is recommended to use before bedtime 1 suppository, which must be inserted deep into the vagina. Betadine candles can be used during menstruation. The course of treatment is usually one week, but in the case of partial effectiveness of Betadine spark rate of application can be extended. Also on prescription single dose can be increased to two suppositories. In a review of Betadine have recommendations regarding the use of sanitary napkins during treatment with this drug.

side effects

Reviews of Betadine confirm good tolerability, but confirmed that in some cases, possible redness, itching, hypersensitivity reactions.

Predisposed patients may be faced with an iodine-induced hyperthyroidism (excessive production of thyroid hormones). Instructions for Betadine warns of the possibility of anaphylactic reactions (dyspnea, hypotension), as well as with the development of dermatitis psoriasiform elements.

Application of Betadine on large areas can trigger an increase sodium levels in the blood, impaired kidney function, metabolic acidosis.


According to the instructions, Betadine is not indicated for:

  • malfunctions or adenoma of the thyroid gland;
  • hyperthyroidism;
  • dermatitis herpetiformis Duhring;
  • renal insufficiency;
  • hypersensitivity to iodine.

Do not use this Betadine children under 1 year old, pregnant and lactating women, as well as before and after the administration of radioactive iodine.

Additional Information

Store this medication in a dark, cool and dry place. Storage Betadine ointment is acceptable at a temperature not exceeding 25 0 C and a humidity of no more than 75%.

Shelf life of the solution and ointment is 3 years, Betadine candles - 2 years.