Bactrim - a combination antimicrobial agent.

Pharmacological action

The structure consists of Bactrim trimethoprim and sulfamethoxazole.

Bactrim exhibits bactericidal activity, activity against streptococci, meningococci, staphylococci, Neisseria gonorrhoeae, Escherichia coli, Salmonella, Vibrio cholerae, Haemophilus, Listeria, pertussis bacillus, fecal enterococci, Klebsiella, Brucella, tsitrobakter, enterobacteria, serratsy, Shigella, intestinal yersiniosis, Morganella, chlamydia, plasmodia, toxoplasma, pathogenic fungi, actinomycetes, histoplasmosis, nocardiosis pathogens, tularemia, legionellosis, pneumocystis pneumonia, coccidioidomycosis.

Exhibit resistance to Bactrim coryneform bacteria, Pseudomonas aeruginosa, the causative agent of tuberculosis viruses.

Therapeutic effect Bactrim lasts 7 hours.

Product form

Bactrim provided in the form of an infusion solution, a syrup, tablets. There is also a suspension Bactrim for internal use and for children.


The instructions Bactrim indications for its use are such diseases:

  • infections of the urogenital system: cystitis, pelonefrit, urethritis, inguinal granuloma, gonorrhea, prostatitis, pyelitis, epididymitis, chancroid, lymphogranuloma venereum;
  • Gastrointestinal infections: cholera, cholangitis, typhoid, gastroenteritis, salmonellonositelstvo, cholecystitis caused enterotoksichnymi strains of Escherichia coli, dysentery, paratyphoid;
  • infection of upper respiratory tract: sinusitis, tonsillitis, otitis media, scarlet fever, laryngitis;
  • respiratory tract infections: Pneumonia, chronic and acute bronchitis, pneumonia, lobar, bronchiectasis, pneumonia;
  • infections of the skin, soft tissue: pyoderma, acne, wound infections, abrasions;
  • osteoartikulyarnye infection;
  • brucellosis;
  • South American blastomycosis;
  • toxoplasmosis;
  • malaria

Instructions for use Bactrim

 Bactrim pills
 According to the instructions Bactrim taken after meals two times a day (usually in the morning, evening), washed down with water.

Bactrim for children older than 12 liters. and adults prescribed to take 4 tablets (or 8 tablespoons of syrup dimensional) - daily dose.

The suspension Bactrim or syrup often given to children up to 12 liters. Bactrim suspension (like syrup) are assigned in such dosages: 6 weeks. up to 5 months. - Half a spoon of two dimensional p. / Day; 6m.- 5 liters. - One measuring spoon two rows. / Day; 5 - 12 liters. - Two spoons, two dimensional p. / Day.

The course of treatment lasts Bactrim under the instruction of 5 days. up to two weeks. If the infection is chronic, treatment Bactrim extend and dose determined by the physician based on the findings of the disease.

Side effects of Bactrim

When using Bactrim suspension, its other pharmacological forms possible adverse reactions from the different systems of the body:

  • urinary: Interstitial nephritis, increased urea concentration, impaired renal function, hematuria, polyuria, toxic nephropathy with oliguria and anuria, hypercreatininemia, crystalluria;
  • hematopoietic neutropenia, anemia, megaloblastic, leukopenia, agranulocytosis, thrombocytopenia;
  • Musculoskeletal: myalgia, arthralgia;
  • Respiratory: pulmonary infiltrates, bronchospasm;
  • Nervous: dizziness, headache. Sometimes - depression, tremors, meningitis, aseptic, apathy, peripheral neuritis;
  • digestive: pseudomembranous enterocolitis, abdominal pain, increased liver transaminases, vomiting, appetite loss, nausea, gastritis, stomatitis, gepatonekroz, diarrhea, hepatitis, glossitis, cholestasis;

It is also possible gipokglikemiya and allergic reactions of varying severity.


According to the instructions Bactrim is not appointed at a sensitivity to it (including sulfanilamides), kidney and liver failure, leukopenia, aplastic anemia and deficiency, pregnancy and lactation, agranulocytosis, deficiency of glucose-6-phosphate dehydrogenase. Children Bactrim may cause hyperbilirubinemia.

Do not prescribe Bactrim preterm children in the first 6 weeks.

The instructions Bactrim stated that he used with caution in diseases of the thyroid gland, bronchial asthma, folic acid deficiency.