Baclofen formula
 Baclofen - tool has a powerful effect on neuromuscular transmission of impulses. It has a strong antidepressant effect.

The pharmacological action of baclofen

Use of Baclofen leads to the following effects on the body:

  • Muscle relaxant;
  • Antispasmodic;
  • Analgesic.

According to the instructions to baclofen, the drug is depressing on monosynaptic and polysynaptic reflexes of the spinal cord, as well as significantly reduces muscle tone.

From the gastrointestinal tract Baclofen Review patients is well absorbed. The maximum effect is reached after administration after 2 - 3 hours. Displays the drug is excreted through the kidneys.

Product form

According to the instructions to baclofen, the drug is available in tablets of 10 mg and 25 mg.

Accordingly, the tablet contains 1 to 10 and 25 mg of the active ingredient (directly baclofen). Tablets are packaged in bottles of 50 pieces, vials are placed in cartons.


The main indications of baclofen are instructions to the following health problems:

  • Multiple sclerosis;
  • Cerebral palsy;
  • Other paralytic syndromes;
  • Other disorders of the brain;
  • Other diseases of the spinal cord;
  • Stroke, not specified as hemorrhage or infarction;
  • Cramps and spasms;
  • Head trauma;
  • Injuries to the spinal cord unspecified level (tumor).

Instructions for use Baclofen

According to the instructions of baclofen taken during a meal. The initial dose for adults and children is 5 mg three times a day. A dose of 1/2 tablet of baclofen at a dosage of 10 mg. Every 3 days the dose is increased. This occurs gradually to avoid overdosing. Under the supervision of a doctor, with strict observance of the instructions to baclofen, increase the dose to achieve the desired therapeutic effect. Usually, for an adult maximum dose of baclofen application reaches from 30 to 75-mg.

This purpose and application of high doses of baclofen, the drug should be used at a dosage of 25 mg. However, as evidenced by the instruction to baclofen, the maximum daily dose should not exceed 100 mg.

For children from 1 to 2 years, under the instruction to baclofen, prescribed, usually no more than 20 mg per day. The daily dose for children 2 hletnego - 6 years of age is from 20 to 30 mg. From 6 to 10 years the use of Baclofen is permissible in the amount of 30 - 60 mg. And after 10 years, uses a different scheme for the use of Baclofen guide based on the weight of the child. Thus, at this age children allow the use of baclofen rate of 1, 5 - 2 mg per 1 kg weight.

Reviews of baclofen have information that the drug should be used cautiously in the following diseases and disorders:

  • Renal impairment and liver;
  • Cerebral stroke;
  • Violation of the respiratory system;
  • Increased tone in the bladder sphincter;
  • The psychotic syndrome;
  • Schizophrenia;
  • Convulsive state;
  • Status confusion.

Numerous reviews of baclofen contain information about the negative consequences of the drug elderly. Therefore, persons over 65 years of age need to be approached with extreme caution in the use of Baclofen.

After the treatment, according to the instructions Baclofen, you must slowly reduce the dose. From reviews of baclofen it is well known that a sharp decrease in dosage can cause the following problems:

  • Convulsions;
  • Restlessness;
  • Anxiety;
  • Hallucinations;
  • Mental disorders;
  • Increasing muscle tone.

Use of Baclofen may adversely affect concentration, so in this period are not advised to drive a car. It is best for the treatment to take a vacation or to conduct inpatient hospital.  Baclofen Tablets

Side effects from the use of Baclofen

Due to the fact that the preparation has a powerful effect, the occurrence of side effects of baclofen is possible. This danger is increased by the non-compliance to baclofen.

Thus, the side effects of baclofen may be different. For example, from the sense organs and the nervous system in a review of baclofen contains the following information about the side effects:

  • Drowsiness or, on the contrary, insomnia;
  • Dizziness;
  • Headache;
  • Fatigue;
  • Weakness;
  • Confusion in the minds;
  • Impaired balance and coordination of movements;
  • Reduced reactivity;
  • Mental stimulation;
  • A state of euphoria;
  • Hallucinations;
  • Depression;
  • Nightmares.

In a review of baclofen there is evidence of serious reactions to the drug action on the part of the cardiovascular system. This reaction serves as the following violations:

  • Arterial hypertension;
  • Rapid heartbeat (tachycardia);
  • Chest pain;
  • Cardiac collapse.

The gastrointestinal tract is also actively responding to the use of baclofen, in violation of the dosage. The response of the organism in this case are the following reactions:

  • Loss of appetite (aversion to food);
  • Changes in taste;
  • Nausea;
  • Constipation or diarrhea;
  • Vomiting;
  • Dyspepsia;
  • Abdominal pain.

In case of violation of the instructions for use of the drug baclofen and without a doctor's appointment possible negative reaction from the urogenital system of the body:

  • Enuresis (incontinence);
  • Spontaneous urination and defecation;
  • Violation of ejaculation;
  • Impotence.

Respiratory system of man, according to the reviews baclofen obtained in patients who react to violation of the instructions for dosage of baclofen, difficulty breathing (nasal congestion), and even the state of suffocation.

Other manifestations of side effects from the use of Baclofen may be signs such as:

  • Muscle pain;
  • A rash on the skin;
  • Itching;
  • Swelling of the extremities;
  • Excessive sweating;
  • Set weight (extra kilos).

If the use of Baclofen accompanied by such signs as chest pain, skin rashes, depression, vomiting, difficulty breathing, should seek immediate medical attention or call an ambulance.

In case of violation of the instructions and approval to baclofen overdose, apply the following urgent measures:

1. Gastric lavage

2. Admission of activated carbon or other absorbent

3. Artificial respiration (in the case of cessation of breathing)

4. Urgent maintenance of the cardiovascular system

Contraindications to baclofen

Contraindications to the use of baclofen are the following situations:

  • Hypersensitivity to the active substance of the drug;
  • Peptic ulcer and (or) the duodenum.

According to responses to baclofen, it is administered during pregnancy only in exceptional cases where the therapeutic effect of the use of Baclofen higher potential risk to the fetus. Breastfeeding and the use of Baclofen incompatible.

Especially careful to be the use of Baclofen for instructions in cases of liver and kidney disease.