Azon - synthetic drug used to treat various forms of depression.
Release form and composition
The drug release in the form of capsules for oral administration the active substance - trazodone. 25 mg, 50 mg and 100 mg.
Azon have antidepressant and sedative (calming) effect. The drug increases the depth and duration of sleep in depressive states and reduces the craving for alcohol. It can be used in the treatment of abstinence, because it eliminates the anxiety and sleep disorders in the acute phase.
Azon is not addictive, is well absorbed from the gastrointestinal tract. The treatment effect observed after 4-10 days after the beginning of reception.
According to the instructions, Azo is used in various forms of depression - endogenous, neurotic, psychotic, somatogenic. The drug is effective in cases where the patient has symptoms of these four:
- Sleep disturbance;
- Reduced interest in the world around them;
- Loss of appetite or bulimia;
- Slow thinking;
- Impaired concentration;
- Reduced sexual activity;
- Anxiety, phobias;
- Obsessive guilt;
- Suicidal thoughts.
It is also testimony to the use of the drug Azon is an acute withdrawal syndrome in alcoholism and benzodiazepine drug dependency. In some cases the use of this drug for the prophylaxis of migraine.
Application Azon is contraindicated for pregnant women, as well as women during lactation. The drug can not be used in patients with hypersensitivity to trazodone, ventricular arrhythmia, tachycardia, a history of priapism, as well as for acute myocardial infarction.
According to the instructions Azon caution should be used in patients who have not attained the age of 18, heart diseases, hypertension (since possible additional hypotensive effect), in patients with renal or hepatic insufficiency.
Dosage and Administration
For the treatment of mild depression drug dosage is 150-200 mg per day, divided into 3 doses, with most of the dose recommended for the evening (before bedtime). In moderate to severe forms of depression, the dosage may be increased to 300 mg per day, the maximum - 600 mg (typically at hospitalization).
The application may be accompanied by Azon some side effects to the central nervous system, usually manifests itself in the form of sleepiness, dizziness, headache, agitation, disorientation, myalgia, incoordination, insomnia, fatigue, tremors, disorientation and dimming of consciousness.
Violations of the cardiovascular system may be manifested as arrhythmia, bradycardia, orthostatic hypotension, conduction disturbances, ventricular fibrillation, lower blood pressure, fainting.
Azon also can cause:
- Nausea, vomiting, diarrhea, dry and bitter taste in the mouth;
- Blurred vision and eye irritation;
- nasal congestion;
- Allergic reactions.
Application Azon changes warfarin, enhances the effects of barbiturates and alcohol. The drug has a hypotensive effect, so in the case of a patient receiving antihypertensive drugs requires correction dose of the latter. Azone is capable of increasing the concentration of digoxin in plasma.
Admission Azon require monitoring by CBC as possible to reduce the total number of leukocytes.
The drug is not contraindicated in prostatic hypertrophy, glaucoma. Treatment of elderly patients should be carried out with the control of blood pressure.
Men undergoing therapy should be warned that in case of inappropriate erections should seek emergency medical attention.
During the treatment of drug Azon should be careful when driving and other activities that require full attention.
On the mechanism of action of drugs are analogues Azon Befol, Azafen, Coaxil, Mirzaten, Alventa, Mirtazonal, inkazan, Despres, agomelatine, Venlaksor, Velafaks, Vensuert, Remeron, Neyroplant, Velaksin, Calixtus, Esprital, Pirazidol, Negrustin, Normazidol, Wellbutrin.
Terms and conditions of storage
Azon is released from pharmacies by prescription. Shelf life of capsules is 5 years.