Atacand - combined medication used for the treatment of hypertension and heart failure.
The active substance of Atacand in hypertension causes prolonged dose-dependent decrease in blood pressure without changes in heart rate. The maximum effect developed after taking the drug for a month and maintained throughout the further treatment. The active substance provides a smooth and effective reduction in blood pressure during the day with a daily intake of the drug once a day.
In the opinion of Atacand after the first dose does not cause severe arterial hypotension and withdrawal effect after cessation of therapy. The effectiveness of Atacand is independent of age and gender of patients.
In addition, the use of Atacand in heart failure as an adjunctive therapy improves left ventricular systolic function and decrease total peripheral vascular resistance and pulmonary capillary pressure.
Atacand produced in the form of round light pink tablets containing 8, 16 and 32 mg of candesartan cilexetil. Excipients - carmellose calcium, magnesium stearate, giproloza, dye red iron dioxide, lactose monohydrate, macrogol, and corn starch. 14 tablets in a blister.
By analogues Atacand containing the same active ingredient, the drug belongs Kandekor.
Indications for use of Atacand
According to the instructions Atacand is used for:
- Heart failure and systolic dysfunction of the left ventricle as adjunctive therapy to ACE inhibitors or in cases of intolerance.
Atacand is contraindicated according to the instructions to apply at:
- Abnormal liver function, or cholestasis;
- Hypersensitivity to the active substance - candesartan tsileksetilu or other components of the tablets Atacand.
Pregnancy and lactation are contraindications to the use of the drug.
Atacand should be taken with caution:
- In severe renal failure;
- At bilateral renal artery stenosis;
- Cerebrovascular diseases and ischemic heart disease;
- After a kidney transplant in history;
- At the age of 18 years.
How to use Atacand
According to the instructions take Atacand with or without food once a day. When hypertension initial dose and maintained regardless of the age of 8 mg per day, and in some cases - 16 mg. If treatment is not carried out leads to lower blood pressure, it is recommended the combined use of Atacand with thiazide diuretics.
Light and moderate renal impairment dose adjustment is not required. If abnormal liver function the initial dose should not exceed 2 mg Atacand day. The maximum antihypertensive effect of the treatment of the drug is achieved within a month of starting treatment.
In heart failure, early treatment take Atacand 4 mg per day. Take a dose can be doubled every two weeks up to 32 mg per day. Atacand Review is effective while the use of other drugs from chronic heart failure - beta-blockers, ACE inhibitors, cardiac glycosides and diuretics.
If necessary, use the analogs Atacand you should consult with your doctor.
The main symptoms of an overdose of Atacand instructions include dizziness and severe hypotension.
Side effects of Atacand
Atacand Review is well tolerated. Side effects that occur while taking the drug, do not depend on the age and the dose received. In the treatment of hypertension often develop weakness, dizziness, respiratory infections, headache, back pain.
When the complex treatment of chronic heart failure of Atacand reviews can cause a marked reduction in blood pressure, leucopenia, neutropenia, renal impairment, nausea, agranulocytosis, angioedema, hyperkalemia, hyponatremia, arthralgia, dizziness, headache, back pain, weakness, rash, myalgia, urticaria, pruritus, renal failure.
Atacand refers to List B drugs and released on the doctor's prescription. The recommended shelf life of the product - 3 years.