Artradol - medicines used to regulate metabolism in cartilage.
Pharmacological action Artradola
Active substance Artradola - Chondroitin sulfate has chondroprotective properties, reduces the activity of the enzymes which is caused by degeneration of the articular cartilage and the effect on calcium-phosphorus metabolism in cartilage.
Chondroitin sulfate also affects the metabolic processes in the cartilage and subchondral bone, stimulates the regeneration and cartilage proteoglycan production by chondrocytes. By synoviocytes and macrophages synovium chondroitin sulfate promotes reduction in synovial fluid ejection pain factors and mediators of inflammation, has a suppressive effect on the secretion of prostaglandin E2 and leukotriene B4 has analgesic and anti-inflammatory properties.
Application Artradola helps normalize development of joint fluid, restores cartilage surface of joints and prevents the collapse of the connective tissue.
According to the instructions, Artradol produce a compacted into a tablet of white or white with a yellowish tinge porous mass for solution for intramuscular injection in vials of 100 mg of 10 pieces. Artradola One ampoule contains 100 mg of sodium chondroitin sulfate.
Artradola analogues of the active substance preparations are:
- Chondroitin Arthritis 750;
- Hondrolayf lyophilisate;
- Hondrolon lyophilisate;
By analogues Artradola mechanism of action and of belonging to a pharmacological group includes:
- Amtolmetin guatsil;
- Diafleks Rompharm;
- Diacerein Mak;
According to the instructions, Artradol used in the treatment of degenerative diseases of joints and spine, namely:
- Primary osteoarthritis;
- Intervertebral osteochondrosis.
According to the instructions, Artradol used as a solution of 100 mg intramuscularly in a day. To prepare the solution, one ampoule of medicament dissolved in 1 ml of water for injection. If the drug was well tolerated, the dose may be increased to four injections of 200 mg. The course of treatment is 25-35 Artradolom injection with possible repeated course after six months.
According to the instructions, the use of Artradola contraindicated in case of hypersensitivity to the drug and in children. With care prescribe medication in pregnancy and lactation, bleeding and thrombophlebitis.
Concomitant use Artradola with indirect fibrinolytic, antiplatelet and anticoagulation leads to strengthening their actions.
According to reviews, Artradol may cause allergic reactions. Also, reviews, Artradol can leave hemorrhage at the injection site.
In accordance with the instructions, Artradol must be stored out of reach of children and protected from light, dry place at room temperature to 20 ° C. Shelf life in compliance with the recommendations is 3 years.