Ampioks is a combined antibiotic spectrum united action oxacillin and ampicillin.
Oxacillin is a semisynthetic penicillin group antibiotic with a bactericidal action against Gram-negative cocci, and Gram-positive organisms. Ampicillin is a semisynthetic penicillin kisloustoychiv, bactericidal effect.
Ampioks by parenteral administration (injection) and well when administered into the blood, bioavailability (delivery into the blood) above, if the drug is taken on an empty stomach. The therapeutic concentration in the blood is kept for 4-6 hours. Plasma protein binding is 20-60%. The half-life ampioks - 2-4 hours, excreted by the kidneys, does not accumulate in tissues.
Ampioks appointed in the following cases:
- infections of the respiratory tract and lungs (pneumonia, bronchitis);
- sore throat;
- inflammation of the renal pelvis (pyelitis);
- inflammation of the renal pelvis and kidney tissue (pyelonephritis);
- inflammation of the gallbladder (cholecystitis);
- inflammation of the bile ducts (cholangitis);
- inflammation of the bladder (cystitis);
- infected wounds, skin infection (pyoderma, etc.);
- inflammation of the inner cavities of the heart (endocarditis);
- sepsis (bacterial infection of the blood);
- postpartum infection;
- burn disease;
- kidney infection;
- prevention and treatment of infections in infants;
- prevention of purulent postoperative complications.
Application ampioks advisable in the case of an unidentified antibiotikogrammy and unallocated exciter.
Before starting treatment with this drug a desirable procedure is to determine the sensitivity of the microflora ampioks that caused the disease.
Using this preparation is orally administered, and Ampioks -sodium - intravenously or intramuscularly. For adults, the daily dose of the latter should not exceed 4 grams and job should be between 0, 5-1 g
For children, the daily dose of the drug is determined based on body weight for children under 1 year administered 0, 1-0, 2 g / kg; children 1-7 years recommended 0, 1 g / kg; children 7-14 years prescribe 0, 05 g / kg; children over 14 years prescribed dose of adults. When severe infections may increase the dose to 1, 5-2 times.
The duration of therapy ampioks determined by a physician, it usually takes 5 to 20 days.
For intramuscular injection, the vial should add 2 ml sterile water jet intravenous - 10-15 mL of sterile water or sodium chloride solution, and an intravenous drip injection - 100-200 ml of sodium chloride solution or 5% glucose. The prepared solution is subject to immediate use, it is unacceptable mixing with other drugs. Time bolus intravenous administration ampioks should be 2-3 minutes, and the rate of drop of input should be within 60-80 drops per minute. Intravenous drug is usually used for a week, then the patient is transferred to intramuscular administration. Application ampioks children as a drip occurs after pre-dilution of the preparation of 5-10% glucose solution in a volume of 30-100 mL.
According to the instructions for use ampioks, the daily dose of the drug when administered orally shall be appointed as follows: Adults and children over 14 years - 2-4 g, for children 3-7 years - 0, 1 mg / kg, for children 7-14 years - 0, 05 mg / kg. The average duration of treatment lasts from one week to two. The daily dose should be divided ampioks four to six receptions.
Negative reactions are possible on ampioks parenteral administration in the form of allergic reactions, pain at the injection site, anaphylactic shock.
For oral application may occur ampioks vomiting, nausea, diarrhea and allergies.
According to the instructions, Ampioks not prescribed for hypersensitivity, lymphocytic leukemia, infectious mononucleosis. Particular caution is needed in the appointment of the drug to children whose mothers have an increased sensitivity to penicillin.
Ampioks Shelf life is two years.
Storage of the drug should be performed in a dry and dark place at room temperature.