Amoxiclav - is a comprehensive means of antibacterial action.
Pharmacological action Amoksiklava
Active ingredients are amoxicillin Amoksiklava - antibiotic penicillin group of broad-spectrum and clavulanic acid, an inhibitor of microorganisms acting beta-lactamase.
The acid prevents the destruction of amoxycillin by formation of inactive and stable compounds with beta-lactamases, which makes it possible to use Amoksiklava in combating infections resistant to amoxicillin.
Form release Amoksiklava
Amoxiclav release tablets 500, 250 mg, powder for suspension of internal use. According to the instructions Amoxiclav release and powder for solution for intravenous administration.
The instructions Amoksiklava stated that it is prescribed for such diseases:
- otitis media;
- chronic, acute sinusitis;
- chronic bronchitis;
- retropharyngeal abscess;
- odontogenic infection;
- infections of joints and bones;
- gynecological infections;
- soft tissue infections, skin;
- urinary tract infections.
There are good reviews Amoksiklava, used in orthopedics, maxillofacial surgery.
It can be used as part of therapy Amoxiclav mixed infections, for prevention of septic complications from the operations of the pelvic organs, kidney, bile ducts, heart, abdomen.
Methods of application Amoksiklava
Amoksiklava tablet is chewed thoroughly before use or dissolved in 100 mL of water with good stirring.
The daily dosage is 375mg tablets Amoxiclav (one tablet) three p. / Day or 625mg two or three p. / Day.
Babies Amoxiclav tablets in such dosages prescribed, if the mass of the body have 40kg and more.
Amoxiclav children up to 3 months. given by 30mg per kilogram of body weight (in terms of amoxicillin). Starting from 3 months, as well as body weight less than 40 kg or 25 mg administered Amoxiclav 20mg per kilogram per day - is for diseases of moderate severity. If the infection is difficult (sinusitis, otitis media, lower respiratory tract lesions, and others.), Children Amoxiclav give 45 or 40 mg per kilogram per day.
The maximum permissible dose for children Amoksiklava a day - 45mg per kilogram of body weight of the child (payment is given for amoxicillin); clavulanic acid - 10mg per kg (in potassium salt form).
According to the instructions Amoxiclav injection administered to children older than 12 liters (or weighing 40 kilograms or more) adults: 1, 2 g every 8 hours. Injections Amoksiklava children from 3 months to 12 liters. administered at 30 mg per kilogram of body weight, and every 8 hours. If the disease runs hard, with a break appoint Amoxiclav 6 hours (up to 3 months to over 8 h., 30 mg per kilogram of body weight). In the first days of life in preterm infants provide Amoxiclav of 30mg / kg every 12 hours.
Treatment of adults and children Amoksiklava usually lasts two weeks.
There are positive reviews Amoksiklava, its use for the prevention of septic complications before surgery. Amoxiclav appoint 1, 2 g intravenously before anesthesia. When prolonged operations administered an additional 1, 2 g Amoksiklava, but no more than four times a day.
Side effects Amoksiklava
Reviews Amoksiklava talk about such possible side effects:
- system of blood: anemia, eosinophilia, thrombocytopenia, agranulocytosis, leukopenia;
- Digestion: diarrhea, flatulence, gastritis, nausea, dyspepsia, glossitis, stomatitis, anorexia, enterocolitis, vomiting;
- Nervous System: anxiety, inappropriate behavior, excitement, convulsions, confusion, insomnia, hyperactivity, dizziness, headache;
- Skin: hives, swelling, rash. Rarely - exfoliative dermatitis, toxic epidermal necrolysis, Stevens - Johnson syndrome, erythema multiforme;
- urinary system: interstitial nephritis, hematuria.
Among other side effects after using Amoksiklava known fever, oral candidiasis and vaginal (yeast).
Follow the instructions Amoxiclav not prescribed for cholestatic jaundice, hepatitis, caused by taking penicillin antibitiotikov. Additionally, contraindicated agent for sensitivity to penicillin drugs, clavulanic acid, amoxicillin, other components Amoksiklava.