Amitriptyline - an antidepressant drug,.

Pharmacological action

 Amitriptyline tablets
 Amitriptyline has a strong sedative, and anti-ulcer effect antibulemicheskoe.

The antidepressant effect develops in 14-28 days after application Amitriptyline.

Product form

Producing a solution, capsules, dragees, pills amitriptyline.

Indications Amitriptyline

The drug is prescribed to treat depression involutional, reactive, endogenous, natural medicinal and developed on the background of alcohol abuse, organic brain damage, accompanied by sleep disturbances, agitation, anxiety.

Known such testimony Amitriptyline: schizophrenic psychoses, mixed emotional disorders, behavioral disorders, nocturnal enuresis (other than that caused by the low tone of the bladder), bulimia nervosa, chronic pain (migraines, atypical facial pain, pain in cancer patients, post-traumatic neuropathy and diabetic rheumatic pain, post-herpetic neuralgia).

There are positive reviews of amitriptyline, used for peptic ulcer gastrointestinal tract, to relieve headaches, migraine prophylaxis.

How to use Amitriptyline

Amitriptyline tablets taken without chewing, the food. The starting dose for adults - 25-50mg take medication for the night. Over 5-6dn. the dosage is increased, adjusted to 150-200mg / day, use them in three steps. The instructions Amitriptyline indicated that the dosage was increased to 300 mg / day, if after two weeks no improvement is observed. If symptoms of depression disappeared, the dosage should be reduced to 50-100 mg / day. Positive reviews of amitriptyline say that good results can be achieved with treatment duration of at least three months.

 Injections of Amitriptyline
 Elderly patients with minor violations of Amitriptyline pills prescribed at a dose of 30-100mg / day, take them at night. After improving the patients are allowed to go on the minimum dosage of 25-50mg / day.

Intravenously or intramuscularly, the drug is administered in a dosage of 20-40mg slowly four p / day, after taking the pills amitriptyline. Treatment lasts 6-8mes.

Amitriptyline on indications neurological pain (including chronic headaches) and for migraine prophylaxis taken in a dosage of 12, 5-100mg / day.

Babies 6-10l when nocturnal enuresis provide 10-20mg of the drug per day, at night; children 11-16l - 25-50mg / day.

For the treatment of depression children 6-12l prescribed according to the instructions Amitriptyline 10-30mg or 1-5mg / kg / day, fractional. Older children take the medication prescribed three p / day for 10 mg.

Side effects

The use of Amitriptyline may cause blurred vision, urination, dry mouth, increased intraocular pressure, increased body temperature, constipation, intestinal obstruction. Judging by the reviews of amitriptyline, these side effects disappear after reducing the dose or after the designated patient addiction to the drug.

In addition, after treatment can be observed weakness, ataxia, fatigue, insomnia, dizziness, nightmares, confusion, irritability, tremor, motor agitation, hallucinations, drowsiness, impaired attention, paresthesia, seizures, arrhythmia, tachycardia, nausea, heartburn, stomatitis, vomiting, anorexia, tongue color change, epigastric discomfort, increased liver enzymes, diarrhea, jaundice, galactorrhoea, changes in potency, libido, testicular swelling, urticaria, pruritus, purpura, hair loss, swollen lymph nodes.


For instructions Amitriptyline is contraindicated in violation of conductivity infarction, severe hypertension, acute kidney, liver, bladder atony, prostatic hypertrophy, paralytic ileus, hypersensitivity, nursing, pregnant women, children up to 6 liters.

Under strict medical supervision should take the drug to patients with bronchial asthma, suffer from manic depression, alcoholism, epilepsy, depression of bone marrow hematopoietic function, hyperthyroidism, angina, heart failure, ocular hypertension, glaucoma closure, schizophrenia.