Aerius - antiallergic  Packing Aerius
 preparation, histamine H1-receptor.

The drug is presented in the form of circular tablets, coated blue sheath, transparent orange syrup.

The active substance Aerius-Desloratadine. Auxiliary components tabletok- microcrystalline cellulose, calcium gidrofosfatadigidrat, corn starch, talc.

Excipients Erius syrup, sorbitol, propylene glycol, anhydrous citric acid, sodium benzoate, sodium citrate dihydrate, dinatriyaedetat flavoring number 15864, sucrose, a coloring agent, purified water.

Pharmacological action

Aerius is an antihistamine - a drug carrying a blockade of histamine receptors in the body that leads to inhibition of allergic reactions. The active substance Aerius selectively acts on neurotransmitters affecting Blistering-congestive reaction of the skin, itching, etc., does not penetrate the blood-brain barrier. Studies have proven that the use of Aerius is able to suppress the body's reaction the following:

  • Production of proinflammatory chemokines and cytokines;
  • The adhesion of eosinophilic granulocytes and chemotaxis;
  • IgE-dependent release of histamine, prostaglandin D2 and leukotriene C4;
  • Increased adhesiveness P-selectin;
  • The development of acute bronhospazmaatopicheskogo character (in experiments involving animals).

The drug has antipruritic, anti-allergic and protivoekssudativnoe actions preventing the appearance and easier for allergic reactions. Aerius effectively relieves spasms of smooth muscles and prevents the occurrence of edema.

Reviews of Aerius not say the emergence of sedative (calming) effect. In addition, clinical studies have shown that taking into Erius dosage of 20 mg / day for 2 weeks, no significant effect on the cardiovascular system. Unlike other antihistamines Erius the efficiency does not affect the use of a fatty meal or grapefruit juice.

Indications Aerius

According to the instructions Erius effective against diseases such as:

  • Allergic rhinitis (including intermittent and persistent);
  • Hay fever, intended for rapid relief (removal of painful phenomena), itching eyes, sneezing, watery eyes, coughing, swelling of the nasal mucosa, conjunctival hyperemia;
  • Chronic idiopathic urticaria.


Application Aerius undesirable persons with hypersensitivity to desloratadine, and other components within the drug. Also, it does not recommend taking Aerius congenital fructose intolerance, presence of diseases associated with malabsorption or glucose-galactose - due to the presence of these substances in the composition of Aerius syrup.

At the moment, the safety profile for pregnant Aerius is not set, so the reception of the drug in women, waiting for the child, is not recommended. Clinically, it found that the active ingredient of the drug passes into breast milk, so breast-feeding while taking Aerius should be discontinued.

With careful use of Aerius should be administered to patients with severe renal insufficiency.

Side effects of Aerius

Side effects  Aerius tablets
 Aerius and unique assets include fatigue, dry mouth, headache, tachycardia, allergic reaction (anaphylactic shock, rash), hepatitis, increased liver enzymes, increased bilirubin in the blood. The feedback to the Aerius while taking the drug by children under 2 years there have been cases of insomnia, diarrhea and chills.

Dosing Aerius

The optimal dose of Aerius instructions for adults and adolescents from 12 years of age is 5 mg per day. The tablet is not recommended to crush, the drug is taken whole with a little liquid. The dosage for children from 2-5 years: 2, 5 ml of syrup for children from 6-11 years of age: 5 ml of the syrup.


In the case of exceeding the recommended dosage of the drug to implement standard measures for the removal of desloratadine from the gastrointestinal tract (administration of activated charcoal, gastric lavage) and spend symptomatic therapy. The drug is not excreted in hemodialysis. In the study of experts, overdose means 9 times on the body does not have a serious negative impact.

Aerius and analogues of the drug

Aerius analogues (drugs-substitutes) are drugs such as the desloratadine, Dezloratadinagemisulfat, Lordestin.

Further information

Eating at the same time with the use of Aerius is not on the efficacy of the drug has significant influence.

According to the instructions Aerius also has no adverse effects on human driving.