Irifrin - symptomatic medication used in ophthalmology to reduce intraocular pressure, and diagnostics.

Pharmacological action

The active substance Irifrin constricts blood vessels of the conjunctiva, the pupil expands and improves the outflow of intraocular fluid.

Mydriasis after single instillation occurs from 10 minutes to one hour and stored depending on the solution: The use of 2, 5% solution - for 2 hours, 10% - action continues until 7 hours.

No effect on the heart and central nervous system.

Thomas Release

The drug is released in the form of colorless transparent eye drops:

Irifrin 2, 5%. 1 ml contains 25 ml of active ingredient phenylephrine hydrochloride. At 0, 4 ml disposable tubes, droppers, 15 tubes in a carton box; 5 ml in plastic or glass bottles.

Irifrin 10%. 1 ml contains 100 ml of active substance phenylephrine hydrochloride. 5 ml plastic or glass vials.

Indications Irifrin

According to the instructions Irifrin used to diagnose:

  • Ophthalmoscopy for control of the rear section of the pelvis;
  • If you suspect a closure glaucoma (provocative tests);
  • Injections of the eyeball.

Also according to the instructions Irifrin drops used to treat glaucoma, tsikliticheskih crises, short-sightedness caused by the visual load, and the "red-eye syndrome", reducing congestion and irritation of the eye membranes.

In surgery the drug is used in vitreoretinal surgery, to improve pupil in preoperative preparation and carrying out laser interventions in the fundus.

In the opinion of Irifrin effective in preventing myopia, and iridocyclitis.


According to the instructions Irifrin is contraindicated in:

  • Thyroid disease (with overproduction of hormones);
  • Narrow-angle or angle-closure glaucoma;
  • Diseases of the cardiovascular system - aortic aneurysm, cardiac arrhythmias, tachycardia and high blood pressure;
  • Individual giperchuvstvitelnsoti to Irifrin or its components;
  • Type 1 diabetes;
  • Tachycardia;
  • Additional mydriasis (in operations with a reduction in total slezoproduktsii or violation of the integrity of tissues of the eyeball);
  • Impaired glucose-6-phosphate dehydrogenase;
  • Hepatic porphyria.

Drops Irifrin not appointed at a constant receiving monoamine oxidase inhibitors, antihypertensive agents, tricyclic antidepressants in children and breast-feeding.

Instructions for use Irifrin

 Irifrin drops
 To diagnose the drug is used only once. When ophthalmoscopy and provocative test in diagnostic procedures.

Irifrin solution 2, 5% was dropped to the conjunctival sac, and in the case of insufficient effect can repeat one hour.

For the differentiation of superficial and deep injection of the eyeball after applying a drop of the drug results were observed after 5 minutes.

For the treatment of glaucoma, and iridocyclitis tsikliticheskogo crisis instill one drop every 8 hours. Depending on the prescribed course of the disease up to 10 days. It can be used as Irifrin 2, 5% and 10%.

With a high visual load and caused her myopia or spasm accommodation apply one drop Irifrin 2, 5% before bedtime. In cases where the myopia progression, the drug can be used three times a day.

In school-age children for the prevention of myopia with high visual load Irifrin instilled one drop before bedtime, during normal visual load - 3 times a week for a month.

When preoperative half an hour before the operation using a 10% drop Irifrin, once in the conjunctival sac.

Side effects

In the opinion of Irifrin can cause various disorders of eye - periorbital edema or conjunctivitis, as well as at the beginning of the application of possible burning sensation and pain in the eye, irritation and discomfort, blurred vision, increased intraocular pressure, lacrimation. Older people may have reactive miosis on the second day of the drug, which takes place with time.

In some cases, after taking Irifrin possible increase in pressure, contact dermatitis, heart palpitations, arrhythmia and tachycardia.

Storage conditions

Irifrin prescription. Shelf life - 2 years. After opening the bottle can be used within a month.