Vaccine Act-HIB

Act-HIB - a vaccine for the prevention of purulent infection.

Release form and composition

Act-HIB produced in powder form (lyophilisate) for preparation of a solution for subcutaneous or intramuscular administration.

The active ingredient - Vaccine for preventing infections caused by Haemophilus influenzae type b.

0, 5 ml (one dose) after dissolving the lyophilisate contains:

  • Polysaccharide Haemophilus influenzae type b (Hib), conjugated to tetanus toxoid - 10 g;
  • Hydroxymethyl aminomethane - 0, 6 mg;
  • Sucrose - 42 5 mg.

The solvent comprises 2 mg of sodium chloride, water for injection - up to 0, 5 ml.


According to the instructions, Act-HIB is used to prevent inflammatory diseases purulent septicheskoggo nature caused by Haemophilus influenzae type b.

The vaccine is allowed to introduce children from 3 months.


Application of Act-HIB is contraindicated in identifying hypersensitive to its components, especially for tetanus toxoid.

If a child is diagnosed the disease in acute or exacerbation of existing chronic illness, delaying vaccination and vaccinate only after 2-4 weeks of full recovery.

In the presence of intestinal infection and mild respiratory illnesses Act-HIB can be administered after the normal body temperature.

Tetanus protein can not be used as a substitute for vaccination against tetanus.

Weak immune response in children with immunodeficiency or undergoing immunosuppressive therapy.

Dosage and Administration

Act-HIB powder before use are mixed with the solvent by shaking, until a clear, colorless solution. Enter drug deep subcutaneous or intramuscular injection.

A single dose of 0, 5 ml. Children under 2 years of solution is injected into the thigh - in the middle third of the anterolateral area. Children older than 2 years old - in the deltoid muscle.

Vaccination is recommended for such a scheme for children under six months do 3 injection with an interval of 1-2 months. Repeated prevention through a 1 year.

If a child is vaccinated for the first time between the ages of 6 months to 1 year, then make two injections with an interval of 1 month. At 1, 5 years do another shot.

If the prevention of Haemophilus influenzae begin between the ages of 1 and 5 years, the Act-HIB, according to instructions, is administered only 1 time.

Side effects

After the application of the Act-HIB at the injection site may occur swelling, soreness, redness, or seal. There are comments indicating the possibility of visiting the child irritability, vomiting, itching, hives, swelling of legs, cramps, fever above 39 ° C.

Premature babies born at 28 weeks or earlier, for several days after the administration of the solution can be observed an increase in the interval between respiratory movements.


It should be noted that the vaccine does not generate a child immunity against meningitis of other origin, and the pathogen Haemophilus influenzae other species.


Act-HIB an analogue of the active substance is a drug Hiberiks.

By the same pharmacological subgroup refers vaccine conjugate Haemophilus influenzae type b.

Terms and conditions of storage

Store at 2-8 ° C. Keep away from children. Shelf life - 3 years.