Nexium - synthetic drug used to reduce the secretion of hydrochloric acid in the treatment of ulcers and erosive lesions of the stomach.
Active substance Nexium affects gastric mucosa and decreases the secretion of hydrochloric acid. The therapeutic effect allows you to use the drug for the healing of erosions, ulcers and stomach inflammation.
Action Nexium develops within hours after its application, and the lasting effect is observed after five days of daily administration.
Nexium discharged as a light pink oblong film-coated tablets in blisters to 7 pieces in two dosages:
- Nexium 20, containing 20 mg of esomeprazole, engraved with "20 mG" on one side;
- Nexium 40, containing 40 mg of esomeprazole, engraved with "40 mG" on one side.
Also, the drug produced in the form of a lyophilisate for solution for intravenous administration of 5 ml vials containing 40 mg of esomeprazole as a white pressed mass.
The most common Indian counterparts Nexium are drugs and Ezoksium Ezolong. These drugs are similar to the main active substance designation and have the same therapeutic effect. Before using the analog Nexium should consult a doctor.
Nexium is used to treat gastroesophageal reflux disease, namely:
- For the treatment of erosive reflux esophagitis;
- As symptomatic treatment of gastroesophageal reflux disease;
- As a long-term maintenance therapy to prevent relapse after healing of erosive reflux esophagitis.
Nexium is also used:
- In a combination therapy for the treatment of gastric ulcer and duodenal ulcer;
- For the treatment and prevention of relapse of peptic ulcers, which is associated with Helicobacter pylori;
- For healing of gastric ulcers, which is associated with nonsteroidal anti-inflammatory drugs;
- To carry out long kislotopodavlyayuschey therapy after suffering bleeding from peptic ulcers;
- With Zollinger-Ellison syndrome and other conditions characterized by pathological hypersecretion, including idiopathic hypersecretion.
Nexium instructions for use is contraindicated in childhood and hypersensitivity to substituted benzimidazoles, esomeprazole or other ingredients of the formulation.
During pregnancy and lactation Nexium is used only on strict conditions due to lack of necessary data on the safety of the drug in these periods.
The drug is contraindicated for use concurrently with atazanavir and nelfinavir.
With careful use of Nexium in patients with renal failure, severe.
In applying the drug should take into account that it can smooth the symptoms of cancer symptoms and delay diagnosis. Therefore, the symptoms of a large spontaneous weight loss, frequent vomiting and dysphagia is necessary to the proper diagnosis.
Care should be taken while the application of Nexium with other drugs because of possible malabsorption of these drugs, the therapeutic effect of the changes and increased side effects.
Instructions for use of Nexium
The duration of treatment and dosage instructions for Nexium dependent disease.
For the treatment of erosive reflux esophagitis take over one month pill Nexium 40. If symptoms remained, treatment can be continued for another 4 weeks. For maintenance therapy to prevent relapse use long one pill Nexium 20.
Nexium for the treatment of gastric ulcer and duodenal ulcer are used in the complex therapy, a single dose in this case is 1 pill Nexium 20, the rate of reception - twice a day for a week.
For long kislotopodavlyayuschey therapy after suffering bleeding from peptic ulcers used for a month on one tablet Nexium 40 per day.
While the use of nonsteroidal anti-inflammatory drugs prescribed Nexium 20 mg or 40 mg daily for two months.
When pathological hypersecretion, including Zollinger-Ellison syndrome and idiopathic hypersecretion, usually prescribed 1 tablet Nexium 40 twice a day.
If the kidney function in the elderly is usually the dose is not adjusted, in hepatic insufficiency a daily dose should not exceed 20 mg.
If it is impossible internal use Nexium is prescribed according to the instructions given by injection once a day by 20-40 mg. Typically, this treatment is short duration and for maintenance therapy should take the drug in pill form.
When using analog Nexium treatment regimen should check with your doctor.
Nexium for reviews often causes abdominal pain and headache, diarrhea, and other digestive disorders.
Less drug causes allergic reactions in the form of dermatitis, itching, rash or hives. Also available insomnia or drowsiness, dizziness, blurred vision, paresthesia, peripheral edema, dry mouth, increased liver enzymes.
It is extremely rare for reviews Nexium cause anaphylactic reactions, bronchospasm, myalgia, hepatitis, arthralgia, malaise, leukopenia, stomatitis, thrombocytopenia, depression, hyponatremia, erythema multiforme, agitation, liver failure, confusion, alopecia, taste disturbance, photosensitivity, gastrointestinal candidiasis tract, sweating.
Nexium - Prescription drug.
Shelf life of the intravenous solution - 2 years, Nexium tablets - 3 years.