Lipoic acid

 Lipoic acid

Lipoic acid - an antioxidant with a tonic effect, which regulates lipid and carbohydrate metabolism.

Pharmacological action

Lipoic acid (thioctic acid or alpha-lipoic acid) - an endogenous antioxidant, capable of binding free radicals in the body.

Acting like vitamins, it stimulates metabolism of cholesterol and improves the trophism of neurons, thereby reducing the concentration of glucose in the blood to overcome the insulin resistance and increased hepatic glycogen.

Alpha-lipoic acid has hypolipidemic, hepatoprotective, hypoglycemic and hypocholesterolemic effect, improves liver function, reduces the impact on it of various toxins, including alcohol.

Using alpha-lipoic acid in the solution for intravenous injection reduces the possibility of adverse reactions.

Product form

Lipoic acid is produced in the form of coated capsules containing from 12 mg to 600 mg of the acid, and concentrate to prepare an intravenous solution or solution for infusion.

Lipoic acid diet used in the composition of biologically active ingredients included in the composition of various drugs and antioxidant complexes.

The best results were recorded with a combination of lipoic acid and carnitine and vitamins of group B.

Indications for use of lipoic acid

Alpha lipoic acid is used according to instructions in diabetic polyneuropathy.

In the opinion of lipoic acid is prescribed to improve the energy metabolism under reduced pressure and anemia.

It is also often used for weight loss lipoic acid, either alone or as part of combination therapy, most often - in conjunction with carnitine.

Carnitine and lipoic acid are part of dietary supplements that promote weight loss due to the acceleration of metabolism.

Effect of lipoic acid for weight loss is enhanced by the other B vitamins

Also according to some studies Carnitine and Lipoic acid may reduce oxidative stress that causes aging, and increase energy production.


Pregnancy, hypersensitivity and lactation are contraindications when using alpha-lipoic acid. Also, the drug is not indicated for children because of the lack of reliable data.

 Lipoic acid and Carnitine

Instructions for use of lipoic acid

A single dose of lipoic acid ingestion of 600 mg. Usually the course of the application is 30 days.

When using intravenous (bolus or slow infusion) administered on day 300-600 mg.

side effects

In the application of lipoic acid for possible reviews various allergic reactions - anaphylactic shock, urticaria, and hypoglycemia.

After intravenous administration of alpha-lipoic acid may be:

  • Convulsions;
  • Petechial hemorrhages in the skin and mucous membranes;
  • Diplopia;
  • Violation of platelet function.

With the rapid introduction of possible sharp rise in intracranial pressure.

In the opinion of Lipoic acid ingestion can cause vomiting, nausea or heartburn.

Lipoic acid while the use of insulin and oral hypoglycemic agents may enhance the hypoglycemic effect.

With simultaneous use of alpha-lipoic acid with cisplatin may decrease its action.

storage conditions

Lipoic Acid without prescription. Shelf life - 3 years.

Note that lipoic acid had a light-sensitive properties, and hence can not be prepared in advance of the ampoule, and it is necessary to extract them from the package just before use.