Brief description of the disease

 Pemphigus skin
 Pemphigus - a severe skin disease, which manifests the formation of bubbles on the surface of the skin and mucous membranes. This process is due to stratification of the epithelium and is characterized by a tendency to spread rapidly due to the merger of several lesions. Causes of pemphigus is not fully understood, which is why treatment of the disease is often ineffective. Especially dangerous pemphigus in children. In the absence of adequate treatment, it can lead to serious complications and even death of the child, although modern medical technology can reduce the number of deaths to a minimum. However, children of all ages are affected infrequently. Much more common viral pemphigus has an effect in those aged 40 to 60 years.

Symptoms of pemphigus

True Pemphigus begins with the appearance of blisters on the skin and mucous membranes. They reach the size of a walnut and is often broken, releasing the contents of clear or bloody. After a break in the skin form of ulceration. Also, there were cases when the bubbles do not burst and fell down, leaving itchy crust.

Seborrheic pemphigus manifests itself differently. Bubbles under this form is usually small. They do not tend to rupture and often shrivel to form a grayish yellow brown.

Viral pemphigus - a disease that is caused by the Coxsackie virus. It is characterized by rashes on the hands and toes, soles and palms. The formation of bubbles deliver pain accompanied by fever and ulceration of the oral mucosa.

Treatment of pemphigus

 Methotrexate - a drug for the treatment of pemphigus
 Due to the fact that the etiology of the disease is unknown, the treatment process is rather complicated and often does not lead to the desired effect. However, to self - is unacceptable, since the disease develops over time and affects more and more areas of the skin, leading to a malfunction of the internal organs and, quite possibly, the death of the patient.

If you are diagnosed pemphigus, treatment is based on the use of hormones both inside and for outdoor use. Hormone is with an eye on the vital indications and possible contraindications are rarely taken into account, since complications pemphigus can lead to fatal consequences. For this reason, even if the normalization of the patient, the daily dose of the hormones is gradually reduced and very carefully until until is reached the minimum dose required to maintain a stable remission.

Good results can achieve a combination of hormones such cytostatic and imunosupresors drugs as azathioprine, methotrexate, and Sandimmun. It should be borne in mind that the funds have individual tolerance and should be used with great caution.

When the diagnosis of pemphigus, the disease is treated with different complementary techniques, in particular, hemosorption and plasmapheresis, ie procedures aimed at cleansing the blood. A positive effect is achieved by the removal of immune complexes from the blood, and other pathogenic immunoglobulin components. In cleansing the blood of toxic substances is also directed photochemotherapy, which consists in the inactivation of blood cells to ultraviolet radiation in combination with G-methoxypsoralen.

As prophylactic agents commonly used drugs, potassium and calcium.

Pemphigus children

In the case of children of damaged skin and mucous membranes are particularly dangerous due to the inadequate implementation of protective mechanisms of the body of the child. Note that pemphigus in newborns is extremely rare. Usually the disease progresses in children aged 5-7 years, and the girls get sick more often than boys.

Pemphigus symptoms are the same as in adults - the appearance of bubbles of different sizes in the face, trunk and extremities with subsequent rupture or desiccation. Itching and other unpleasant sensations are virtually absent. With timely and adequate treatment quickly comes remission.

Malignant pemphigus in children is rare, but is accompanied by severe consequences - weight loss, asthenia, the emergence of secondary infections, fever and septic complications of the kidneys, lungs, and cardiovascular system.

Any methods of treatment used on children should be used with extreme caution, especially in the use of hormones and cytostatics because for them there is often idiosyncrasy.