Hyperlipidemia is a violation of lipid metabolism with a high content in their blood. The disorder is a risk factor for cardiovascular disease and pancreatitis.
Causes and symptoms of hyperlipidemia
Hyperlipidemia can cause deposition of atherosclerotic plaques and the development of atherosclerosis. An excess amount affects the active lipid deposit formation of cholesterol and calcium. When a large excess of lipids deteriorating blood circulation and increases the likelihood of developing coronary artery disease, heart attack, aortic aneurysm and cerebral circulatory disorders.
Causes of hyperlipidemia can be violations of blood pressure, obesity, diabetes and old age. Development of the disease contribute to a sedentary lifestyle, kidney and thyroid cancer, smoking and drinking alcoholic beverages.
Symptoms hyperlipidemia are bland in nature, and the disease is detected using biochemical blood analysis. Hyperlipidemia can appear as a hereditary disease, and the risk of its occurrence increases after 40 years.
Some drugs cause increased accumulation of lipids in the body. These include: estrogens, contraceptives and hormone drugs, diuretic drugs.
Types of hyperlipidemia
There are five main types of hyperlipidemia, which differ by factors of the disease and the degree of progression. General classification lipid disorders was established scientist D. Fredrickson in 1965 and adopted as the official version of the World Health Organisation.
The first type of hyperlipidemia is the most rare and develops LPL deficiency of protein, and also causes increase of chylomicron.
Hyperlipidemia second type is the most common form of the disease and is accompanied by a high content of triglycerides.
Lipid disorders such as hereditary or sporadic caused by genetic mutations and familial predisposition to the development of cardiovascular diseases.
A particular subtype of hyperlipidemia is a violation of clearance, as well as the high content of acetyl-CoA and triglycerides.
The third type of hyperlipidemia manifested in an increased amount and chylomicron LPPP caused by disorders of LDL receptors.
The fourth and fifth type of diseases are rare and most are accompanied by an increased concentration of triglycerides.
Treatment of hyperlipidemia
Treatment of hyperlipidemia begin by establishing the type of disease and the level of lipids in the body. An important component of treatment is a low-fat diet, which seeks to reduce the amount of lipids and to maintain their normal levels in the body.
Also attending doctor prescribes special physical exercise to reduce cholesterol and triglycerides. Removing excess weight, regular physical activity and the elimination of bad habits will help to significantly reduce the amount of fat.
In the treatment of hyperlipidemia drugs include the following medications:
- statins reduce cholesterol and prevent its deposition in the liver;
- Bile drugs;
- Vitamin B5.
In patients 50 years after treatment of hyperlipidemia should be integrated with a combination of medication, a special diet, exercise and therapeutic cleansing procedures.