Avamys is a hormonal drug decongestant for local use in diseases of the nasal cavity.
Release form and composition
Inflammatory action Avamys delivers its constituent active ingredient - fluticasone furoate (synthetic glucocorticosteroid).
Active drug made in the form of a nasal spray containing a homogeneous white suspension. By using a single dose of total bioavailability (the ability to be absorbed) drugs is about 0, 5%. Drug binding to plasma proteins is 99%. Metabolism occurs in the liver into inactive metabolites, derived mainly faeces.
Produced spray Avamys 30, 60 or 120 doses per vial.
The drug is indicated for the symptomatic treatment of allergic rhinitis, which manifests itself as a seasonal or year-round. Also in adenoids, to reduce swelling of the mucous.
According to the instructions, Avamys is not assigned in the following cases:
- When individual sensitivity to the drug;
- Patients who have previously received treatment with ritonavir;
- Children under two years.
Precautions Avamys assigned to patients with severe hepatic impairment, as well as pregnant women. During lactation the drug administered in the lowest effective doses.
Dosage and Administration
Spray assigned only for intranasal use (injection through the nose). Use of the drug should be carried out regularly without missing doses.
Clinical studies indicate that there is a measurable impact medication after 7-8 hours after injection dose. The development of the maximum therapeutic effect occurs within three days of application Avamys.
Before the first use of the drug vial should be shaken well, remove the cap and press the button six times dispenser. Such actions are necessary in order to adjust the correct dosage for later use spray. Dosage adjustment is also required if the drug is not used during the last month.
According to the instructions, Avamys must be injected into a pre-cleaned nasal passages. Hold the bottle upright, the head should be tilted slightly forward, then gently put into the nasal passage and the tip of the bottle while breathing in, press the dispenser. Exhale after use Avamys done through the mouth.
Dosage spray Avamys:
- Adults and adolescents older than 12 years - 2 injection into each nasal passage 1 time per day, after a therapeutic effect the dose should be reduced to 1 injection into each nasal passage;
- Children aged 2 to 12 years - 1 injection into each nasal passage 1 time per day, if necessary for the period to achieve the desired effect, the dose can be increased to 2
The duration of treatment determined by the physician, based on the duration of exposure to the allergen and the patient's condition.
Comments about Avamys confirm the possibility of such adverse effects as:
- Ulcerative lesions of the nose;
- Nose bleed;
- Rash, pruritus, urticaria;
- Angioedema, anaphylactic shock;
- The delay in development in children after prolonged use.
You can change the pharmacokinetics of fluticasone furoate in patients with significant liver impairment.
The use Avamys has no effect on the ability to manage complex mechanisms and driving vehicles.
Analogues of the drug on the active ingredients do not.
Analogs of Avamys has a therapeutic effect (treatment of rhinitis, including allergic): Aqua Maris, Allergoferon, Allerzhi, Berlikort, Vibrocil, Vividrin, Galazolin, Gistalong, Grippostad Reno, Dexamethasone, Diazolin, Dlyanos, Doxycycline, Dr. Theiss Nazolin, Zodak, Intal, ketotifen, Klarisens, Claritin, Koldakt, xylometazoline, Lordestin, Morenazal, Nazivin, Nasonex, Naphthyzinum, Olint, prednisolone, Rinzai, Sanorin, Suprastin, Tavegil, Farmazolin, Fervex spray cold, Tsetirinaks, Tsetrin Erbisol and others.
Terms and conditions of storage
The drug should be stored at 15 to 30 ° C, avoiding contact with direct sunlight.
According to the instructions, Avamys can be used within 3 years from the date of manufacture. After the first use of the drug should be used within two months after this period is considered unsuitable.