Dopamine belongs to the clinical and pharmacological group adrenomimeticheskih and dopaminomimetic drugs.
The pharmacological action of dopamine
Dopamine - effective hypertensive and cardiotonic agent.
The duration of treatment and the dose appoints only doctor, self-treatment is strictly forbidden to engage in, because each unit has its own properties.
Typically, a low dose, which is equal to 0, 5-3 mcg / kg / min, mean one that acts largely on dopamine receptors, stimulating expansion mesenteric, cerebral, renal, and coronary vessels. Due to the specific effect on the peripheral receptors drug helps reduce renal vascular resistance, as well as to increase their circulation.
Low and medium dose dopamine can stimulate postsynaptic adrenergic receptors, and therefore increase the minute volume of blood (IOC) and reaches a maximum positive effect.
High doses can cause narrowing of the renal vessels and increase heart rate, PR. Home therapeutic effect occurs within 5 minutes after taking the drug.
Dopamine is produced in the form of a concentrate, which is used for preparing a solution for intravenous administration.
According to the instructions, Dopamine has such evidence:
- acute cardiovascular insufficiency of diverse origin;
- infectious-toxic, anaphylactic, postoperative, hypovolemic and cardiogenic shock;
Analyzing the instructions in the dopamine, can be identified such Contraindications: ventricular fibrillation, pheochromocytoma, increased sensitivity to the drug, and hypertrophic obstructive cardiomyopathy.
Dopamine Guide: how to use
The dosage may be installed exclusively on an individual basis, it depends on the magnitude of the blood pressure, the severity of the shock and the reaction which may occur on administration of dopamine. To improve myocardial contractility and increase diuresis, the drug is administered at 100-250 mg / min infusion. If necessary, the dose may be increased, but must not exceed the maximum permissible - 1, 5 mg / min.
For children the dose is 4-6 mg / kg / min.
The course of treatment lasts for up to 28 days.
As a result of receiving dopamine may have backfired on the part of the digestive system, manifested in vomiting, bleeding from the gastrointestinal tract and nausea.
Also, can negatively affect the use of dopamine in the cardiovascular system that can respond to bradycardia and tachycardia, cramps, impaired patency, supraventricular and ventricular arrhythmias, decreased or increased blood pressure.
Also taking the drug can be accompanied by local allergic reactions, problems with the central nervous system.
Dopamine should be stored in a dark and inaccessible to children, temperature which is 15-25
Dopamine is released in pharmacies with a prescription.