Arimidex - an anticancer drug used to treat breast cancer in postmenopausal women.
Action Arimidex is aimed at reducing the level of estradiol in women. The drug has no androgenic, progestogenic and estrogenic activity. The therapeutic effect of Arimidex on responses of experts is highly effective in the treatment of cancers gormonozavisimvyh.
Arimidex produce as white round tablets containing 1 mg anastrozole. Excipients - karboksimetilenkrahmal sodium, magnesium stearate, lactose monohydrate, povidone and purified water. 14 tablets in blister packs.
Indications for use of Arimidex
According to the instructions Arimidex is used to treat breast cancer in postmenopausal women, as well as an adjuvant therapy for early breast cancer gormonopolozhitelnogo, including after tamoxifen therapy.
Arimidex is contraindicated according to the instructions to apply at:
- Severe renal insufficiency and hepatic failure moderate and severe;
- Concomitant therapy with tamoxifen;
- Hypersensitivity to the Arimidex.
Arimidex on the instructions contraindicated during lactation and pregnancy, as well as children. The drug is not intended for the treatment of pre-menopausal women.
Dosing instructions for Arimidex
Arimidex by instructions permanently take one tablet once a day, preferably at the same time. If signs of disease progression receiving Arimidex should be discontinued. As adjuvant therapy is recommended to take the drug for 5 years.
Adjusting the dose of Arimidex is not required at a moderate degree of renal dysfunction and mild liver function abnormalities.
Arimidex interaction data with other antineoplastic agents available. Concomitant use of tamoxifen reduces the therapeutic effect of Arimidex. Do not take the medication simultaneously with drugs containing estrogen.
Arimidex on responses often causes flushing, skin rash, carpal tunnel syndrome, nausea and diarrhea, headaches, thinning hair, asthenia. Much less when using the drug observed arthralgia, vaginal dryness and sleepiness.
In the opinion of Arimidex are least likely to cause vaginal bleeding, urticaria, anorexia, angioneurotic edema, vomiting, hypercholesterolemia, erythema multiforme, anaphylactic shock.
Arimidex belongs to the drugs List B and released only by prescription. The recommended shelf life - 5 years.