Amaryl - a drug designed to lower blood sugar in diabetes of the second type.
Release form and composition
The drug is available in tablet dosage oval 1, 2, 3 and 4 mg. The active drug substance is glimepiride.
According to the instructions, Amaryl is prescribed for type 2 diabetes (non-insulin dependent diabetes).
The active ingredient glimepiride stimulates the production of insulin by the pancreas and its entry into the blood. Insulin, in turn, reduces the amount of sugar in the blood. Glimepiride improves potassium metabolism in cells, and helps to prevent the formation of atherosclerotic plaque on the vessel walls.
In accordance with the instructions, Amaryl is contraindicated in the following diseases:
- Type 1 diabetes (insulin-dependent);
- Diabetic ketoacidosis (a complication of diabetes type 1);
- Severe diseases of the kidneys and liver;
- Diabetic coma and precoma preceding it;
- Glucose-galactose malabsorption, lactase deficiency, galactose intolerance;
- Children's age;
- Individual intolerance to any component of the formulation;
- Pregnancy and lactation.
Dosage and Administration
According to the instructions, Amaryl should be taken orally without chewing, immediately before breakfast or during, drinking plenty of water (at least ½ cup). Receiving drugs must be linked to food intake, otherwise maybe a critical reduction in blood sugar levels.
The dosage for each patient individually selected by the attending physician, depending upon the level of blood sugar.
Begin treatment is usually with a minimum dose - 1 mg per day. Depending on the patient's doctor may gradually (every 1-2 weeks) increase the dose of Amara following scheme: 1-2-3-4-6 mg. The most common dosage - 1-4 mg per day.
If the patient has forgotten to take the daily rate of the drug, the next admission should not be to increase the dosage. Actions in case of accidental abuse treatment regimen should be negotiated with the doctor in advance.
During the application of Amar needs control over blood sugar levels.
The most common side effect of the drug - hypoglycemia (drop in blood sugar levels below normal). In addition, the use of Amara can cause the following negative effects:
- Since the cardiovascular system: hypertension, tachycardia, angina pectoris, bradycardia;
- From the hematopoietic system: thrombocytopenia, leukopenia, anemia, pancytopenia, granulocytopenia, agranulocytosis;
- From the nervous system: drowsiness or insomnia, headache, increased aggressiveness, decreased reaction rate, anxiety, loss of consciousness, speech disorders, convulsions, tremors in the limbs;
- On the part of the digestive system: nausea, vomiting, diarrhea, feeling of heaviness in the stomach, cholestasis, jaundice, hepatitis;
- Allergic reactions: itching, rash, allergic vasculitis, skin rash;
- Impaired vision.
In case of side effects after taking Amaro and deterioration of general condition should immediately consult a doctor.
During the course of treatment is recommended to regularly monitor blood glucose levels and liver function.
Use of the drug requires increased caution when working with complex mechanisms and management of transport.
The structural analogs include drugs Amaro: Glemaz, Glyumedeks, Meglimid, Diamerid, Glemauno.
Conditions and terms
The drug should be stored in a dry, dark place at a temperature not exceeding 25 ° C.
Shelf life is 3 years Amaro from the production date.