Vasari relates to preparations having antihypertensive (blood pressure lowering) properties. The active substance Vasari - valsartan.
The active substance Vasari has hypotensive effect, that is, the ability to reduce blood pressure. The effect of the drug is observed for two hours, the maximum reduction in blood pressure occurs within 4-5 hours after taking Vasari. The ability to reduce the pressure remains Vasari hours after ingestion.
The maximum effect of regular intake of Vasari occurs within 2-4 weeks after the start of treatment and may persist throughout the course.
To enhance the effectiveness of the pressure reduction may be taking Vasari H, in which there is an increased content of hydrochlorothiazide.
Vasari is not addictive, abrupt withdrawal of the drug did not lead to negative consequences.
Bioavailability is 23%. The active substance Vasari quickly absorbed into the bloodstream and binds to blood proteins. Excreted in the feces, a small portion (13%) in the urine.
The product is produced in tablets, coated tablets, intended for ingestion, 40, 80 and 160 mg of Vasari. Depending on the concentration of active ingredient tablets differ in color: 40 mg - yellow 80 mg - 160 mg and pink Vazario - too yellow.
Vazario H - hydrochlorothiazide is added to the preparation in an amount from 0 0125 to 0 025 g, whereby enhanced hypotensive effect Vazario N.
According to the instructions, Vasari used for hypertension (high blood pressure), as well as diseases of the heart and blood vessels with chronic heart failure.
Instructions for use and dose Vasari
Take 160 mg Vasari once a day. If necessary, the dose may be increased to 320 mg per day. Simultaneous reception with other drugs to lower blood pressure.
In chronic heart failure Vasari begin to take a dose of 40 mg, then gradually increase to 160 mg per day Vasari.
After myocardial infarction Vasari prescribe a dose of 20 mg, then gradually increase to 160 mg per day Vasari.
According to the instructions to the Vasari, the drug can cause such adverse effects:
- Orthostatic hypotension;
- Heart failure;
- abdominal pain;
- Pain in the back;
In very rare cases, renal failure, angioedema, gastroenteritis.
According to the instructions, Vasari is contraindicated in these states:
- Hypersensitivity to the primary or secondary components of the drug;
- Abnormal liver function in severe;
- Renal dysfunction;
- Violation of the outflow of bile;
- Pregnancy and breast-feeding.
If overdose is possible excessive lowering of blood pressure. The main methods of care for overdose: the adoption of the horizontal position of the patient, intravenous saline solutions.